| Identification |
|---|
| HMDB Protein ID
| CDBP02150 |
| Secondary Accession Numbers
| Not Available |
| Name
| Urea transporter 1 |
| Description
| Not Available |
| Synonyms
|
- Solute carrier family 14 member 1
- Urea transporter, erythrocyte
|
| Gene Name
| SLC14A1 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in urea transmembrane transporter activity |
| Specific Function
| Specialized low-affinity urea transporter. Mediates urea transport in erythrocytes.
|
| GO Classification
|
| Biological Process |
| ammonium transmembrane transport |
| Cellular Component |
| integral to plasma membrane |
| Component |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| amide transmembrane transporter activity |
| urea transmembrane transporter activity |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| transporter activity |
| Molecular Function |
| urea transmembrane transporter activity |
| water transmembrane transporter activity |
| ammonium transmembrane transporter activity |
| Process |
| amide transport |
| urea transport |
| establishment of localization |
| transport |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| 18q11-q12 |
| SNPs
| SLC14A1 |
| Gene Sequence
|
>1170 bp
ATGGAGGACAGCCCCACTATGGTTAGAGTGGACAGCCCCACTATGGTTAGGGGTGAAAAC
CAGGTTTCGCCATGTCAAGGGAGAAGGTGCTTCCCCAAAGCTCTTGGCTATGTCACCGGT
GACATGAAAAAACTTGCCAACCAGCTTAAAGACAAACCCGTGGTGCTCCAGTTCATTGAC
TGGATTCTCCGGGGCATATCCCAAGTGGTGTTCGTCAACAACCCCGTCAGTGGAATCCTG
ATTCTGGTAGGACTTCTTGTTCAGAACCCCTGGTGGGCTCTCACTGGCTGGCTGGGAACA
GTGGTCTCCACTCTGATGGCCCTCTTGCTCAGCCAGGACAGGTCATTAATAGCATCTGGG
CTCTATGGCTACAATGCCACCCTGGTGGGAGTACTCATGGCTGTCTTTTCGGACAAGGGA
GACTATTTCTGGTGGCTGTTACTCCCTGTATGTGCTATGTCCATGACTTGCCCAATTTTC
TCAAGTGCATTGAATTCCATGCTCAGCAAATGGGACCTCCCCGTCTTCACCCTCCCTTTC
AACATGGCGTTGTCAATGTACCTTTCAGCCACAGGACATTACAATCCGTTCTTTCCAGCC
AAACTGGTCATACCTATAACTACAGCTCCAAATATCTCCTGGTCTGACCTCAGTGCCCTG
GAGTTGTTGAAATCTATACCAGTGGGAGTTGGTCAGATCTATGGCTGTGATAATCCATGG
ACAGGGGGCATTTTCCTGGGAGCCATCCTACTCTCCTCCCCACTCATGTGCCTGCATGCT
GCCATAGGATCATTGCTGGGCATAGCAGCGGGACTCAGTCTTTCAGCCCCATTTGAGGAC
ATCTACTTTGGACTCTGGGGTTTCAACAGCTCTCTGGCCTGCATTGCAATGGGAGGAATG
TTCATGGCGCTCACCTGGCAAACCCACCTCCTGGCTCTTGGCTGTGCCCTGTTCACGGCC
TATCTTGGAGTCGGCATGGCAAACTTTATGGCTGAGGTTGGATTGCCAGCTTGTACCTGG
CCCTTCTGTTTGGCCACGCTATTGTTCCTCATCATGACCACAAAAAATTCCAACATCTAC
AAGATGCCCCTCAGTAAAGTTACTTATCCTGAAGAAAACCGCATCTTCTACCTGCAAGCC
AAGAAAAGAATGGTGGAAAGCCCTTTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 389 |
| Molecular Weight
| 48341.29 |
| Theoretical pI
| 6.531 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Urea transporter 1
MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID
WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG
LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF
NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW
TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM
FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY
KMPLSKVTYPEENRIFYLQAKKRMVESPL
|
| External Links |
|---|
| GenBank ID Protein
| 193784782 |
| UniProtKB/Swiss-Prot ID
| Q13336 |
| UniProtKB/Swiss-Prot Entry Name
| UT1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK123681 |
| GeneCard ID
| SLC14A1 |
| GenAtlas ID
| SLC14A1 |
| HGNC ID
| HGNC:10918 |
| References |
|---|
| General References
| Not Available |