<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">2141</id>
  <cancdbp-id>CDBP02140</cancdbp-id>
  <name>Fatty-acid amide hydrolase 1</name>
  <uniprot-id>O00519</uniprot-id>
  <uniprot-name>FAAH1_HUMAN</uniprot-name>
  <enzyme type="boolean">true</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Enzyme</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>FAAH</gene-name>
  <num-residues type="integer">579</num-residues>
  <molecular-weight type="decimal">63065.28</molecular-weight>
  <theoretical-pi type="decimal">7.665</theoretical-pi>
  <general-function>Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor</general-function>
  <specific-function>Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids></pdb-ids>
  <genbank-gene-id>AF098019</genbank-gene-id>
  <genbank-protein-id>4249693</genbank-protein-id>
  <genecard-id>FAAH</genecard-id>
  <chromosome-location>1</chromosome-location>
  <locus>1p35-p34</locus>
  <geneatlas-id>FAAH</geneatlas-id>
  <hgnc-id>HGNC:3553</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:2166</kegg-id>
  <meta-cyc-id>HS04139-MONOMER</meta-cyc-id>
  <ncbi-sequence-ids>NP_001432.2:NM_001441.2</ncbi-sequence-ids>
  <tissue-specificity>Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate.
</tissue-specificity>
  <cofactor></cofactor>
  <subunit>Homodimer
</subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:07:02Z</created-at>
  <updated-at type="dateTime">2020-06-12T23:07:02Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">0</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

