Identification |
HMDB Protein ID
| CDBP02132 |
Secondary Accession Numbers
| Not Available |
Name
| Long-chain fatty acid transport protein 6 |
Description
| Not Available |
Synonyms
|
- FATP-6
- Fatty acid transport protein 6
- Fatty-acid-coenzyme A ligase, very long-chain 2
- Solute carrier family 27 member 6
- VLCSH1
- Very long-chain acyl-CoA synthetase homolog 1
- hVLCS-H1
|
Gene Name
| SLC27A6 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in catalytic activity |
Specific Function
| Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart |
GO Classification
|
Function |
catalytic activity |
Process |
metabolic process |
|
Cellular Location
|
- Cell membrane
- Membrane
- Multi-pass membrane protein (Potential)
- sarcolemma
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q23.3 |
SNPs
| SLC27A6 |
Gene Sequence
|
>1860 bp
ATGCTGCTGTCATGGCTAACAGTTCTAGGGGCTGGAATGGTCGTCCTGCACTTCTTGCAG
AAACTCCTGTTCCCTTACTTTTGGGATGACTTCTGGTTCGTGTTGAAGGTGGTGCTCATT
ATAATTCGGCTGAAGAAGTATGAAAAGAGAGGGGAGCTGGTGACTGTGCTGGATAAATTC
TTGAGTCATGCCAAAAGACAACCTCGGAAACCTTTCATCATCTATGAGGGAGACATCTAC
ACCTATCAGGATGTAGACAAAAGGAGCAGCAGAGTGGCCCATGTCTTCCTGAACCATTCC
TCTCTGAAAAAGGGGGACACGGTGGCTCTGCTGATGAGCAATGAGCCGGACTTCGTTCAC
GTGTGGTTCGGCCTCGCCAAGCTGGGCTGCGTGGTGGCCTTTCTCAACACCAACATTCGC
TCCAACTCCCTCCTGAATTGCATCCGCGCCTGTGGGCCCAGAGCCCTAGTGGTGGGCGCA
GATTTGCTTGGAACGGTAGAAGAAATCCTTCCAAGCCTCTCAGAAAATATCAGTGTTTGG
GGGATGAAAGATTCTGTTCCACAAGGTGTAATTTCACTCAAAGAAAAACTGAGCACCTCA
CCTGATGAGCCCGTGCCACGCAGCCACCATGTTGTCTCACTCCTCAAGTCTACTTGTCTT
TACATTTTTACCTCTGGAACAACAGGTCTACCAAAAGCAGCTGTGATTAGTCAGCTGCAG
GTTTTAAGGGGTTCTGCTGTCCTGTGGGCTTTTGGTTGTACTGCTCATGACATTGTTTAT
ATAACCCTTCCTCTGTATCATAGTTCAGCAGCTATCCTGGGAATTTCTGGATGTGTTGAG
TTGGGTGCCACTTGTGTGTTAAAGAAGAAATTTTCAGCAAGCCAGTTTTGGAGTGACTGC
AAGAAGTATGATGTGACTGTGTTTCAGTATATTGGAGAACTTTGTCGCTACCTTTGCAAA
CAATCTAAGAGAGAAGGAGAAAAGGATCATAAGGTGCGTTTGGCAATTGGAAATGGCATA
CGGAGTGATGTATGGAGAGAATTTTTAGACAGATTTGGAAATATAAAGGTGTGTGAACTT
TATGCAGCTACCGAATCAAGCATATCTTTCATGAACTACACTGGGAGAATTGGAGCAATT
GGGAGAACAAATTTGTTTTACAAACTTCTTTCCACTTTTGACTTAATAAAGTATGACTTT
CAGAAAGATGAACCCATGAGAAATGAGCAGGGTTGGTGTATTCATGTGAAAAAAGGAGAA
CCTGGACTTCTCATTTCTCGAGTGAATGCAAAAAATCCCTTCTTTGGCTATGCTGGGCCT
TATAAGCACACAAAAGACAAATTGCTTTGTGATGTTTTTAAGAAGGGAGATGTTTACCTT
AATACTGGAGACTTAATAGTCCAGGATCAGGACAATTTCCTTTATTTTTGGGACCGTACT
GGAGACACTTTCAGATGGAAAGGAGAAAATGTCGCAACCACTGAGGTTGCTGATGTTATT
GGAATGTTGGATTTCATACAGGAAGCAAACGTCTATGGTGTGGCTATATCAGGTTATGAA
GGAAGAGCAGGAATGGCTTCTATTATTTTAAAACCAAATACATCTTTAGATTTGGAAAAA
GTTTATGAACAAGTTGTAACATTTCTACCAGCTTATGCTTGTCCACGATTTTTAAGAATT
CAGGAAAAAATGGAAGCAACAGGAACATTCAAACTATTGAAGCATCAGTTGGTGGAAGAT
GGATTTAATCCACTGAAAATTTCTGAACCACTTTACTTCATGGATAACTTGAAAAAGTCT
TATGTTCTACTGACCAGGGAACTTTATGATCAAATAATGTTAGGGGAAATAAAACTTTAA
|
Protein Properties |
Number of Residues
| 619 |
Molecular Weight
| 70111.0 |
Theoretical pI
| 8.66 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Long-chain fatty acid transport protein 6
MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF
LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH
VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW
GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ
VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC
KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL
YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE
PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT
GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK
VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS
YVLLTRELYDQIMLGEIKL
|
External Links |
GenBank ID Protein
| 4768275 |
UniProtKB/Swiss-Prot ID
| Q9Y2P4 |
UniProtKB/Swiss-Prot Entry Name
| S27A6_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF064254 |
GeneCard ID
| SLC27A6 |
GenAtlas ID
| SLC27A6 |
HGNC ID
| HGNC:11000 |
References |
General References
| Not Available |