Showing Protein Rho-related GTP-binding protein Rho6 (CDBP02129)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02129
Secondary Accession Numbers Not Available
Name Rho-related GTP-binding protein Rho6
Description Not Available
Synonyms
  1. Rho family GTPase 1
  2. Rnd1
Gene Name RND1
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments
GO Classification
Component
cell part
intracellular
Function
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
purine nucleotide binding
binding
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasm
  4. Cytoplasmic side
  5. cytoskeleton
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q12
SNPs RND1
Gene Sequence 
>699 bp
ATGAAGGAGAGACGGGCCCCCCAGCCAGTCGTGGCCAGATGTAAGCTCGTTCTGGTCGGG
GACGTGCAGTGTGGGAAGACCGCGATGTTGCAAGTGTTAGCGAAGGATTGCTATCCAGAG
ACCTATGTGCCCACCGTGTTCGAAAATTACACAGCCTGTTTGGAGACAGAGGAACAGAGG
GTGGAGCTTAGTCTCTGGGATACCTCAGGATCTCCCTACTACGATAATGTCCGTCCACTC
TGCTACAGCGACTCGGATGCAGTATTACTATGTTTTGACATCAGCCGTCCAGAGACAGTG
GACAGCGCACTGAAGAAGTGGAGGACAGAAATCCTAGATTATTGTCCCAGCACCCGCGTT
TTGCTCATTGGCTGCAAGACAGACCTGCGAACAGACCTGAGTACTCTGATGGAGCTGTCC
CACCAGAAGCAGGCGCCCATCTCCTATGAGCAGGGTTGTGCAATAGCAAAGCAGCTGGGT
GCAGAAATCTACCTGGAAGGCTCAGCTTTCACCTCAGAAAAGAGCATCCACAGCATCTTT
CGGACGGCATCCATGCTGTGTCTGAACAAGCCTAGCCCACTGCCCCAGAAGAGCCCTGTC
CGAAGCCTCTCCAAACGACTGCTCCACCTCCCCAGTCGCTCTGAACTCATCTCTTCTACC
TTCAAGAAGGAAAAGGCCAAAAGCTGTTCCATTATGTGA
Protein Properties
Number of Residues 232
Molecular Weight 26055.8
Theoretical pI 8.03
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Rho-related GTP-binding protein Rho6
MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
GenBank ID Protein 1546902
UniProtKB/Swiss-Prot ID Q92730
UniProtKB/Swiss-Prot Entry Name RND1_HUMAN
PDB IDs Not Available
GenBank Gene ID Y07923
GeneCard ID RND1
GenAtlas ID RND1
HGNC ID HGNC:18314
References
General References Not Available