Identification |
HMDB Protein ID
| CDBP02123 |
Secondary Accession Numbers
| Not Available |
Name
| Myosin regulatory light chain 12A |
Description
| Not Available |
Synonyms
|
- MLC-2B
- Myosin RLC
- Myosin regulatory light chain 2, nonsarcomeric
- Myosin regulatory light chain MRLC3
|
Gene Name
| MYL12A |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in calcium ion binding |
Specific Function
| Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion |
GO Classification
|
Function |
binding |
calcium ion binding |
ion binding |
cation binding |
metal ion binding |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 18p11.31 |
SNPs
| MYL12A |
Gene Sequence
|
>516 bp
ATGTCGAGCAAAAGAACAAAGACCAAGACCAAGAAGCGCCCTCAGCGTGCAACATCCAAT
GTGTTTGCTATGTTTGACCAGTCACAGATTCAGGAGTTCAAAGAGGCCTTCAACATGATT
GATCAGAACAGAGATGGTTTCATCGACAAGGAAGATTTGCATGATATGCTTGCTTCATTG
GGGAAGAATCCAACTGATGAGTATCTAGATGCCATGATGAATGAGGCTCCAGGCCCCATC
AATTTCACCATGTTCCTCACCATGTTTGGTGAGAAGTTAAATGGCACAGATCCTGAAGAT
GTCATCAGAAATGCCTTTGCTTGCTTTGATGAAGAAGCAACTGGCACCATACAGGAAGAT
TACTTGAGAGAGCTGCTGACAACCATGGGGGATCGGTTTACAGATGAGGAAGTGGATGAG
CTGTACAGAGAAGCACCTATTGATAAAAAGGGGAATTTCAATTACATCGAGTTCACACGC
ATCCTGAAACATGGAGCCAAAGACAAAGATGACTGA
|
Protein Properties |
Number of Residues
| 171 |
Molecular Weight
| 19794.0 |
Theoretical pI
| 4.4 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Myosin regulatory light chain 12A
MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL
GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED
YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
|
External Links |
GenBank ID Protein
| 16741043 |
UniProtKB/Swiss-Prot ID
| P19105 |
UniProtKB/Swiss-Prot Entry Name
| ML12A_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC016372 |
GeneCard ID
| MYL12A |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |