Identification
HMDB Protein ID CDBP02123
Secondary Accession Numbers Not Available
Name Myosin regulatory light chain 12A
Description Not Available
Synonyms
  1. MLC-2B
  2. Myosin RLC
  3. Myosin regulatory light chain 2, nonsarcomeric
  4. Myosin regulatory light chain MRLC3
Gene Name MYL12A
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion
GO Classification
Function
binding
calcium ion binding
ion binding
cation binding
metal ion binding
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 18p11.31
SNPs MYL12A
Gene Sequence
>516 bp
ATGTCGAGCAAAAGAACAAAGACCAAGACCAAGAAGCGCCCTCAGCGTGCAACATCCAAT
GTGTTTGCTATGTTTGACCAGTCACAGATTCAGGAGTTCAAAGAGGCCTTCAACATGATT
GATCAGAACAGAGATGGTTTCATCGACAAGGAAGATTTGCATGATATGCTTGCTTCATTG
GGGAAGAATCCAACTGATGAGTATCTAGATGCCATGATGAATGAGGCTCCAGGCCCCATC
AATTTCACCATGTTCCTCACCATGTTTGGTGAGAAGTTAAATGGCACAGATCCTGAAGAT
GTCATCAGAAATGCCTTTGCTTGCTTTGATGAAGAAGCAACTGGCACCATACAGGAAGAT
TACTTGAGAGAGCTGCTGACAACCATGGGGGATCGGTTTACAGATGAGGAAGTGGATGAG
CTGTACAGAGAAGCACCTATTGATAAAAAGGGGAATTTCAATTACATCGAGTTCACACGC
ATCCTGAAACATGGAGCCAAAGACAAAGATGACTGA
Protein Properties
Number of Residues 171
Molecular Weight 19794.0
Theoretical pI 4.4
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Myosin regulatory light chain 12A
MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL
GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED
YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
GenBank ID Protein 16741043
UniProtKB/Swiss-Prot ID P19105
UniProtKB/Swiss-Prot Entry Name ML12A_HUMAN
PDB IDs Not Available
GenBank Gene ID BC016372
GeneCard ID MYL12A
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available