Identification
HMDB Protein ID CDBP02120
Secondary Accession Numbers Not Available
Name Interferon beta precursor
Description Not Available
Synonyms
  1. Fibroblast interferon
  2. IFN-beta
Gene Name IFNB1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Has antiviral, antibacterial and anticancer activities
GO Classification
Component
extracellular region
Function
cytokine activity
hematopoietin/interferon-class (d200-domain) cytokine receptor binding
signal transducer activity
receptor binding
Process
response to biotic stimulus
defense response
response to stimulus
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9p21
SNPs IFNB1
Gene Sequence
>564 bp
ATGACCAACAAGTGTCTCCTCCAAATTGCTCTCCTGTTGTGCTTCTCCACTACAGCTCTT
TCCATGAGCTACAACTTGCTTGGATTCCTACAAAGAAGCAGCAATTTTCAGTGTCAGAAG
CTCCTGTGGCAATTGAATGGGAGGCTTGAATACTGCCTCAAGGACAGGATGAACTTTGAC
ATCCCTGAGGAGATTAAGCAGCTGCAGCAGTTCCAGAAGGAGGACGCCGCATTGACCATC
TATGAGATGCTCCAGAACATCTTTGCTATTTTCAGACAAGATTCATCTAGCACTGGCTGG
AATGAGACTATTGTTGAGAACCTCCTGGCTAATGTCTATCATCAGATAAACCATCTGAAG
ACAGTCCTGGAAGAAAAACTGGAGAAAGAAGATTTCACCAGGGGAAAACTCATGAGCAGT
CTGCACCTGAAAAGATATTATGGGAGGATTCTGCATTACCTGAAGGCCAAGGAGTACAGT
CACTGTGCCTGGACCATAGTCAGAGTGGAAATCCTAAGGAACTTTTACTTCATTAACAGA
CTTACAGGTTACCTCCGAAACTGA
Protein Properties
Number of Residues 187
Molecular Weight 22294.0
Theoretical pI 8.91
Pfam Domain Function
Signals
  • ["1-21"]
Transmembrane Regions Not Available
Protein Sequence
>Interferon beta precursor
MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD
IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK
TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR
LTGYLRN
GenBank ID Protein 32638
UniProtKB/Swiss-Prot ID P01574
UniProtKB/Swiss-Prot Entry Name IFNB_HUMAN
PDB IDs
GenBank Gene ID V00534
GeneCard ID IFNB1
GenAtlas ID IFNB1
HGNC ID HGNC:5434
References
General References Not Available