Identification |
HMDB Protein ID
| CDBP02120 |
Secondary Accession Numbers
| Not Available |
Name
| Interferon beta precursor |
Description
| Not Available |
Synonyms
|
- Fibroblast interferon
- IFN-beta
|
Gene Name
| IFNB1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Not Available |
Specific Function
| Has antiviral, antibacterial and anticancer activities |
GO Classification
|
Component |
extracellular region |
Function |
cytokine activity |
hematopoietin/interferon-class (d200-domain) cytokine receptor binding |
signal transducer activity |
receptor binding |
Process |
response to biotic stimulus |
defense response |
response to stimulus |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:9 |
Locus
| 9p21 |
SNPs
| IFNB1 |
Gene Sequence
|
>564 bp
ATGACCAACAAGTGTCTCCTCCAAATTGCTCTCCTGTTGTGCTTCTCCACTACAGCTCTT
TCCATGAGCTACAACTTGCTTGGATTCCTACAAAGAAGCAGCAATTTTCAGTGTCAGAAG
CTCCTGTGGCAATTGAATGGGAGGCTTGAATACTGCCTCAAGGACAGGATGAACTTTGAC
ATCCCTGAGGAGATTAAGCAGCTGCAGCAGTTCCAGAAGGAGGACGCCGCATTGACCATC
TATGAGATGCTCCAGAACATCTTTGCTATTTTCAGACAAGATTCATCTAGCACTGGCTGG
AATGAGACTATTGTTGAGAACCTCCTGGCTAATGTCTATCATCAGATAAACCATCTGAAG
ACAGTCCTGGAAGAAAAACTGGAGAAAGAAGATTTCACCAGGGGAAAACTCATGAGCAGT
CTGCACCTGAAAAGATATTATGGGAGGATTCTGCATTACCTGAAGGCCAAGGAGTACAGT
CACTGTGCCTGGACCATAGTCAGAGTGGAAATCCTAAGGAACTTTTACTTCATTAACAGA
CTTACAGGTTACCTCCGAAACTGA
|
Protein Properties |
Number of Residues
| 187 |
Molecular Weight
| 22294.0 |
Theoretical pI
| 8.91 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Interferon beta precursor
MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD
IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK
TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR
LTGYLRN
|
External Links |
GenBank ID Protein
| 32638 |
UniProtKB/Swiss-Prot ID
| P01574 |
UniProtKB/Swiss-Prot Entry Name
| IFNB_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| V00534 |
GeneCard ID
| IFNB1 |
GenAtlas ID
| IFNB1 |
HGNC ID
| HGNC:5434 |
References |
General References
| Not Available |