Identification |
HMDB Protein ID
| CDBP02100 |
Secondary Accession Numbers
| Not Available |
Name
| Mitochondrial carnitine/acylcarnitine carrier protein |
Description
| Not Available |
Synonyms
|
- CAC
- Carnitine/acylcarnitine translocase
- Solute carrier family 25 member 20
|
Gene Name
| SLC25A20 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in transporter activity |
Specific Function
| Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
|
GO Classification
|
Biological Process |
small molecule metabolic process |
carnitine shuttle |
cellular lipid metabolic process |
regulation of fatty acid oxidation |
Cellular Component |
integral to membrane |
mitochondrial inner membrane |
Component |
organelle inner membrane |
mitochondrial inner membrane |
membrane |
cell part |
organelle membrane |
Function |
binding |
transporter activity |
Process |
establishment of localization |
transport |
transmembrane transport |
|
Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Oxidation of Branched Chain Fatty Acids | | Not Available | Beta Oxidation of Very Long Chain Fatty Acids | | | Adrenoleukodystrophy, X-linked | | Not Available | Carnitine-acylcarnitine translocase deficiency | | Not Available | Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids | | Not Available |
|
Gene Properties |
Chromosome Location
| 3 |
Locus
| 3p21.31 |
SNPs
| SLC25A20 |
Gene Sequence
|
>906 bp
ATGGCCGACCAGCCAAAACCCATCAGCCCGCTCAAGAACCTGCTGGCCGGCGGCTTTGGC
GGCGTGTGCCTGGTGTTCGTCGGTCACCCTCTGGACACGGTCAAGGTCCGACTGCAGACA
CAGCCACCGAGTTTGCCTGGACAACCTCCCATGTACTCTGGGACCTTTGACTGTTTCCGG
AAGACTCTTTTTAGAGAGGGCATCACGGGGCTATATCGGGGAATGGCTGCCCCTATCATC
GGGGTCACTCCCATGTTTGCCGTGTGCTTCTTTGGGTTTGGTTTGGGGAAGAAACTACAA
CAGAAACACCCAGAAGATGTGCTCAGCTATCCCCAGCTTTTTGCAGCTGGGATGTTATCT
GGCGTATTCACCACAGGAATCATGACTCCTGGAGAACGGATCAAGTGCTTATTACAGATT
CAGGCTTCTTCAGGAGAAAGCAAGTACACTGGTACCTTGGACTGTGCAAAGAAGCTGTAC
CAGGAGTTTGGGATCCGAGGCATCTACAAAGGGACTGTGCTTACCCTTATGCGAGATGTC
CCAGCTAGTGGAATGTATTTCATGACATATGAATGGCTGAAAAATATCTTCACTCCGGAG
GGAAAGAGGGTCAGTGAGCTCAGTGCCCCTCGGATCTTGGTGGCTGGGGGCATTGCAGGG
ATCTTCAACTGGGCTGTGGCAATCCCCCCAGATGTGCTCAAGTCTCGATTCCAGACTGCA
CCTCCTGGGAAATATCCTAATGGTTTCAGAGATGTGCTGAGGGAGCTGATCCGGGATGAA
GGAGTCACATCCTTGTACAAAGGGTTCAATGCAGTGATGATCCGAGCCTTCCCAGCCAAT
GCGGCCTGTTTCCTTGGCTTTGAAGTTGCCATGAAGTTCCTTAATTGGGCCACCCCCAAC
TTGTGA
|
Protein Properties |
Number of Residues
| 301 |
Molecular Weight
| 32943.46 |
Theoretical pI
| 9.405 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Mitochondrial carnitine/acylcarnitine carrier protein
MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFR
KTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLS
GVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDV
PASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTA
PPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPN
L
|
External Links |
GenBank ID Protein
| 2765075 |
UniProtKB/Swiss-Prot ID
| O43772 |
UniProtKB/Swiss-Prot Entry Name
| MCAT_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| Y10319 |
GeneCard ID
| SLC25A20 |
GenAtlas ID
| SLC25A20 |
HGNC ID
| HGNC:1421 |
References |
General References
| Not Available |