| Identification |
|---|
| HMDB Protein ID
| CDBP02100 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mitochondrial carnitine/acylcarnitine carrier protein |
| Description
| Not Available |
| Synonyms
|
- CAC
- Carnitine/acylcarnitine translocase
- Solute carrier family 25 member 20
|
| Gene Name
| SLC25A20 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transporter activity |
| Specific Function
| Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
|
| GO Classification
|
| Biological Process |
| carnitine shuttle |
| cellular lipid metabolic process |
| regulation of fatty acid oxidation |
| small molecule metabolic process |
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| binding |
| transporter activity |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Oxidation of Branched Chain Fatty Acids |    | Not Available | | Beta Oxidation of Very Long Chain Fatty Acids |    |  | | Adrenoleukodystrophy, X-linked |    | Not Available | | Carnitine-acylcarnitine translocase deficiency |    | Not Available | | Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3p21.31 |
| SNPs
| SLC25A20 |
| Gene Sequence
|
>906 bp
ATGGCCGACCAGCCAAAACCCATCAGCCCGCTCAAGAACCTGCTGGCCGGCGGCTTTGGC
GGCGTGTGCCTGGTGTTCGTCGGTCACCCTCTGGACACGGTCAAGGTCCGACTGCAGACA
CAGCCACCGAGTTTGCCTGGACAACCTCCCATGTACTCTGGGACCTTTGACTGTTTCCGG
AAGACTCTTTTTAGAGAGGGCATCACGGGGCTATATCGGGGAATGGCTGCCCCTATCATC
GGGGTCACTCCCATGTTTGCCGTGTGCTTCTTTGGGTTTGGTTTGGGGAAGAAACTACAA
CAGAAACACCCAGAAGATGTGCTCAGCTATCCCCAGCTTTTTGCAGCTGGGATGTTATCT
GGCGTATTCACCACAGGAATCATGACTCCTGGAGAACGGATCAAGTGCTTATTACAGATT
CAGGCTTCTTCAGGAGAAAGCAAGTACACTGGTACCTTGGACTGTGCAAAGAAGCTGTAC
CAGGAGTTTGGGATCCGAGGCATCTACAAAGGGACTGTGCTTACCCTTATGCGAGATGTC
CCAGCTAGTGGAATGTATTTCATGACATATGAATGGCTGAAAAATATCTTCACTCCGGAG
GGAAAGAGGGTCAGTGAGCTCAGTGCCCCTCGGATCTTGGTGGCTGGGGGCATTGCAGGG
ATCTTCAACTGGGCTGTGGCAATCCCCCCAGATGTGCTCAAGTCTCGATTCCAGACTGCA
CCTCCTGGGAAATATCCTAATGGTTTCAGAGATGTGCTGAGGGAGCTGATCCGGGATGAA
GGAGTCACATCCTTGTACAAAGGGTTCAATGCAGTGATGATCCGAGCCTTCCCAGCCAAT
GCGGCCTGTTTCCTTGGCTTTGAAGTTGCCATGAAGTTCCTTAATTGGGCCACCCCCAAC
TTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 301 |
| Molecular Weight
| 32943.46 |
| Theoretical pI
| 9.405 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Mitochondrial carnitine/acylcarnitine carrier protein
MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFR
KTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLS
GVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDV
PASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTA
PPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPN
L
|
| External Links |
|---|
| GenBank ID Protein
| 2765075 |
| UniProtKB/Swiss-Prot ID
| O43772 |
| UniProtKB/Swiss-Prot Entry Name
| MCAT_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Y10319 |
| GeneCard ID
| SLC25A20 |
| GenAtlas ID
| SLC25A20 |
| HGNC ID
| HGNC:1421 |
| References |
|---|
| General References
| Not Available |