Identification
HMDB Protein ID CDBP02098
Secondary Accession Numbers Not Available
Name Calsenilin
Description Not Available
Synonyms
  1. A-type potassium channel modulatory protein 3
  2. DRE-antagonist modulator
  3. DREAM
  4. KChIP3
  5. Kv channel-interacting protein 3
Gene Name KCNIP3
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasm
  4. Golgi apparatus
  5. Endoplasmic reticulum
  6. Nucleus (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q21.1
SNPs KCNIP3
Gene Sequence
>771 bp
ATGCAGCCGGCTAAGGAAGTGACAAAGGCGTCGGACGGCAGCCTCCTGGGGGACCTCGGG
CACACACCACTTAGCAAGAAGGAGGGTATCAAGTGGCAGAGGCCGAGGCTCAGCCGCCAG
GCTTTGATGAGATGCTGCCTGGTCAAGTGGATCCTGTCCAGCACAGCCCCACAGGGCTCA
GATAGCAGCGACAGTGAGCTGGAGCTGTCCACGGTGCGCCACCAGCCAGAGGGGCTGGAC
CAGCTGCAGGCCCAGACCAAGTTCACCAAGAAGGAGCTGCAGTCTCTCTACAGGGGCTTT
AAGAATGAGTGTCCCACGGGCCTGGTGGACGAAGACACCTTCAAACTCATTTACGCGCAG
TTCTTCCCTCAGGGAGATGCCACCACCTATGCACACTTCCTCTTCAACGCCTTTGATGCG
GACGGGAACGGGGCCATCCACTTTGAGGACTTTGTGGTTGGCCTCTCCATCCTGCTGCGG
GGCACAGTCCACGAGAAGCTCAAGTGGGCCTTTAATCTCTACGACATTAACAAGGATGGC
TACATCACCAAAGAGGAGATGCTGGCCATCATGAAGTCCATCTATGACATGATGGGCCGC
CACACCTACCCCATCCTGCGGGAGGACGCGCCGGCGGAGCACGTGGAGAGGTTCTTCGAG
AAAATGGACCGGAACCAGGATGGGGTAGTGACCATTGAAGAGTTCCTGGAGGCCTGTCAG
AAGGATGAGAACATCATGAGCTCCATGCAGCTGTTTGAGAATGTCATCTAG
Protein Properties
Number of Residues 256
Molecular Weight 29231.0
Theoretical pI 5.06
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Calsenilin
MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGS
DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQ
FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG
YITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQ
KDENIMSSMQLFENVI
GenBank ID Protein 62822203
UniProtKB/Swiss-Prot ID Q9Y2W7
UniProtKB/Swiss-Prot Entry Name CSEN_HUMAN
PDB IDs Not Available
GenBank Gene ID AC009238
GeneCard ID KCNIP3
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available