Showing Protein Progressive ankylosis protein homolog (CDBP02092)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02092
Secondary Accession Numbers Not Available
Name Progressive ankylosis protein homolog
Description Not Available
Synonyms
  1. ANK
Gene Name ANKH
Protein Type Transporter
Biological Properties
General Function Involved in phosphate transmembrane transporter activity
Specific Function Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter
GO Classification
Component
integral to membrane
cell part
membrane part
intrinsic to membrane
Function
inorganic anion transmembrane transporter activity
phosphate transmembrane transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
anion transmembrane transporter activity
Process
establishment of localization
transport
phosphate transport
anion transport
inorganic anion transport
ion transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5p15.1
SNPs ANKH
Gene Sequence 
>1479 bp
ATGGTGAAATTCCCGGCGCTCACGCACTACTGGCCCCTGATCCGGTTCTTGGTGCCCCTG
GGCATCACCAACATAGCCATCGACTTCGGGGAGCAGGCCTTGAACCGGGGCATTGCTGCT
GTCAAGGAGGATGCAGTCGAGATGCTGGCCAGCTACGGGCTGGCGTACTCCCTCATGAAG
TTCTTCACGGGTCCCATGAGTGACTTCAAAAATGTGGGCCTGGTGTTTGTGAACAGCAAG
AGAGACAGGACCAAAGCCGTCCTGTGTATGGTGGTGGCAGGGGCCATCGCTGCCGTCTTT
CACACACTGATAGCTTATAGTGATTTAGGATACTACATTATCAATAAACTGCACCATGTG
GACGAGTCGGTGGGGAGCAAGACGAGAAGGGCCTTCCTGTACCTCGCCGCCTTTCCTTTC
ATGGACGCAATGGCATGGACCCATGCTGGCATTCTCTTAAAACACAAATACAGTTTCCTG
GTGGGATGTGCCTCAATCTCAGATGTCATAGCTCAGGTTGTTTTTGTAGCCATTTTGCTT
CACAGTCACCTGGAATGCCGGGAGCCCCTGCTCATCCCGATCCTCTCCTTGTACATGGGC
GCACTTGTGCGCTGCACCACCCTGTGCCTGGGCTACTACAAGAACATTCACGACATCATC
CCTGACAGAAGTGGCCCGGAGCTGGGGGGAGATGCAACAATAAGAAAGATGCTGAGCTTC
TGGTGGCCTTTGGCTCTAATTCTGGCCACACAGAGAATCAGTCGGCCTATTGTCAACCTC
TTTGTTTCCCGGGACCTTGGTGGCAGTTCTGCAGCCACAGAGGCAGTGGCGATTTTGACA
GCCACATACCCTGTGGGTCACATGCCATACGGCTGGTTGACGGAAATCCGTGCTGTGTAT
CCTGCTTTCGACAAGAATAACCCCAGCAACAAACTGGTGAGCACGAGCAACACAGTCACG
GCAGCCCACATCAAGAAGTTCACCTTCGTCTGCATGGCTCTGTCACTCACGCTCTGTTTC
GTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGAC
TTTGCCTTTGCAGAACTCTGTGTTGTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCA
GTCACAGTGAGGGCGCATCTCACCGGGTGGCTGATGACACTGAAGAAAACCTTCGTCCTT
GCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTAC
CTGGGGGTGCACGGTGCGACCCTGGGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAA
TCCACCATGGTCGCCATCGCTGCGTGCTATGTCTACCGGAAGCAGAAAAAGAAGATGGAG
AATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAG
GTGACAGACATCGTGGAAATGAGAGAGGAGAATGAATAA
Protein Properties
Number of Residues 492
Molecular Weight 54240.4
Theoretical pI 7.97
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["86-106", "132-152", "159-179", "190-210", "327-347", "351-371", "404-426", "430-452"]
Protein Sequence 
>Progressive ankylosis protein homolog
MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMK
FFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHV
DESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILL
HSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSF
WWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVY
PAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVD
FAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY
LGVHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENESATEGEDSAMTDMPPTEE
VTDIVEMREENE
GenBank ID Protein 16905507
UniProtKB/Swiss-Prot ID Q9HCJ1
UniProtKB/Swiss-Prot Entry Name ANKH_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_054027.4
GeneCard ID ANKH
GenAtlas ID ANKH
HGNC ID HGNC:15492
References
General References Not Available