Identification |
HMDB Protein ID
| CDBP02073 |
Secondary Accession Numbers
| Not Available |
Name
| Keratinocyte growth factor |
Description
| Not Available |
Synonyms
|
- FGF-7
- Fibroblast growth factor 7
- HBGF-7
- Heparin-binding growth factor 7
- KGF
|
Gene Name
| FGF7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in growth factor activity |
Specific Function
| Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation |
GO Classification
|
Function |
binding |
protein binding |
receptor binding |
growth factor activity |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 15q21.2 |
SNPs
| FGF7 |
Gene Sequence
|
>585 bp
ATGCACAAATGGATACTGACATGGATCCTGCCAACTTTGCTCTACAGATCATGCTTTCAC
ATTATCTGTCTAGTGGGTACTATATCTTTAGCTTGCAATGACATGACTCCAGAGCAAATG
GCTACAAATGTGAACTGTTCCAGCCCTGAGCGACACACAAGAAGTTATGATTACATGGAA
GGAGGGGATATAAGAGTGAGAAGACTCTTCTGTCGAACACAGTGGTACCTGAGGATCGAT
AAAAGAGGCAAAGTAAAAGGGACCCAAGAGATGAAGAATAATTACAATATCATGGAAATC
AGGACAGTGGCAGTTGGAATTGTGGCAATCAAAGGGGTGGAAAGTGAATTCTATCTTGCA
ATGAACAAGGAAGGAAAACTCTATGCAAAGAAAGAATGCAATGAAGATTGTAACTTCAAA
GAACTAATTCTGGAAAACCATTACAACACATATGCATCAGCTAAATGGACACACAACGGA
GGGGAAATGTTTGTTGCCTTAAATCAAAAGGGGATTCCTGTAAGAGGAAAAAAAACGAAG
AAAGAACAAAAAACAGCCCACTTTCTTCCTATGGCAATAACTTAA
|
Protein Properties |
Number of Residues
| 194 |
Molecular Weight
| 22509.1 |
Theoretical pI
| 9.51 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Keratinocyte growth factor
MHKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYME
GGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLA
MNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTK
KEQKTAHFLPMAIT
|
External Links |
GenBank ID Protein
| 186739 |
UniProtKB/Swiss-Prot ID
| P21781 |
UniProtKB/Swiss-Prot Entry Name
| FGF7_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| M60828 |
GeneCard ID
| FGF7 |
GenAtlas ID
| FGF7 |
HGNC ID
| HGNC:3685 |
References |
General References
| Not Available |