| Identification |
|---|
| HMDB Protein ID
| CDBP02049 |
| Secondary Accession Numbers
| Not Available |
| Name
| Epididymal secretory protein E1 |
| Description
| Not Available |
| Synonyms
|
- He1
- Human epididymis-specific protein 1
- Niemann-Pick disease type C2 protein
|
| Gene Name
| NPC2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cholesterol binding |
| Specific Function
| May be involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q24.3 |
| SNPs
| NPC2 |
| Gene Sequence
|
>456 bp
ATGCGTTTCCTGGCAGCTACATTCCTGCTCCTGGCGCTCAGCACCGCTGCCCAGGCCGAA
CCGGTGCAGTTCAAGGACTGCGGTTCTGTGGATGGAGTTATAAAGGAAGTGAATGTGAGC
CCATGCCCCACCCAACCCTGCCAGCTGAGCAAAGGACAGTCTTACAGCGTCAATGTCACC
TTCACCAGCAATATTCAGTCTAAAAGCAGCAAGGCCGTGGTGCATGGCATCCTGATGGGC
GTCCCAGTTCCCTTTCCCATTCCTGAGCCTGATGGTTGTAAGAGTGGAATTAACTGCCCT
ATCCAAAAAGACAAGACCTATAGCTACCTGAATAAACTACCAGTGAAAAGCGAATATCCC
TCTATAAAACTGGTGGTGGAGTGGCAACTTCAGGATGACAAAAACCAAAGTCTCTTCTGC
TGGGAAATCCCAGTACAGATCGTTTCTCATCTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 151 |
| Molecular Weight
| 16570.1 |
| Theoretical pI
| 7.77 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Epididymal secretory protein E1
MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVT
FTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYP
SIKLVVEWQLQDDKNQSLFCWEIPVQIVSHL
|
| External Links |
|---|
| GenBank ID Protein
| 12803417 |
| UniProtKB/Swiss-Prot ID
| P61916 |
| UniProtKB/Swiss-Prot Entry Name
| NPC2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC002532 |
| GeneCard ID
| NPC2 |
| GenAtlas ID
| NPC2 |
| HGNC ID
| HGNC:14537 |
| References |
|---|
| General References
| Not Available |