<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">2044</id>
  <cancdbp-id>CDBP02043</cancdbp-id>
  <name>5-hydroxytryptamine receptor 2A</name>
  <uniprot-id>P28223</uniprot-id>
  <uniprot-name>5HT2A_HUMAN</uniprot-name>
  <enzyme type="boolean">false</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Receptor</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>HTR2A</gene-name>
  <num-residues type="integer">471</num-residues>
  <molecular-weight type="decimal">52602.6</molecular-weight>
  <theoretical-pi type="decimal">7.72</theoretical-pi>
  <general-function>Involved in G-protein coupled receptor protein signaling pathway</general-function>
  <specific-function>This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production</specific-function>
  <signal-regions type="array">
    <signal-region>["None"]</signal-region>
  </signal-regions>
  <transmembrane-regions type="array">
    <transmembrane-region>["76-99", "111-132", "148-171", "192-215", "234-254", "325-346", "363-384"]</transmembrane-region>
  </transmembrane-regions>
  <pdb-ids nil="true"/>
  <genbank-gene-id>X57830</genbank-gene-id>
  <genbank-protein-id>36431</genbank-protein-id>
  <genecard-id>HTR2A</genecard-id>
  <chromosome-location>Chromosome:1</chromosome-location>
  <locus>13q14-q21</locus>
  <geneatlas-id>HTR2A</geneatlas-id>
  <hgnc-id>HGNC:5293</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id nil="true"/>
  <meta-cyc-id nil="true"/>
  <ncbi-sequence-ids nil="true"/>
  <tissue-specificity nil="true"/>
  <cofactor nil="true"/>
  <subunit nil="true"/>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:07:01Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:27:27Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">1</receptor>
  <metal-binding type="integer">0</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

