| Identification |
|---|
| HMDB Protein ID
| CDBP02009 |
| Secondary Accession Numbers
| Not Available |
| Name
| Copper transport protein ATOX1 |
| Description
| Not Available |
| Synonyms
|
- Metal transport protein ATX1
|
| Gene Name
| ATOX1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
|
| GO Classification
|
| Biological Process |
| response to oxidative stress |
| cellular copper ion homeostasis |
| copper ion transport |
| Cellular Component |
| cytosol |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| Molecular Function |
| copper chaperone activity |
| Process |
| transport |
| ion transport |
| cation transport |
| metal ion transport |
| establishment of localization |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Mineral absorption | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| 5q32 |
| SNPs
| ATOX1 |
| Gene Sequence
|
>207 bp
ATGCCGAAGCACGAGTTCTCTGTGGACATGACCTGTGGAGGCTGTGCTGAAGCTGTCTCT
CGGGTCCTCAATAAGCTTGGAGGAGTTAAGTATGACATTGACCTGCCCAACAAGAAGGTC
TGCATTGAATCTGAGCACAGCATGGACACTCTGCTTGCAACCCTGAAGAAAACAGGAAAG
ACTGTTTCCTACCTTGGCCTTGAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 68 |
| Molecular Weight
| 7401.575 |
| Theoretical pI
| 7.239 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Copper transport protein ATOX1
MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTLLATLKKTGK
TVSYLGLE
|
| External Links |
|---|
| GenBank ID Protein
| 158259587 |
| UniProtKB/Swiss-Prot ID
| O00244 |
| UniProtKB/Swiss-Prot Entry Name
| ATOX1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK293063 |
| GeneCard ID
| ATOX1 |
| GenAtlas ID
| ATOX1 |
| HGNC ID
| HGNC:798 |
| References |
|---|
| General References
| Not Available |