| Identification |
|---|
| HMDB Protein ID
| CDBP01997 |
| Secondary Accession Numbers
| Not Available |
| Name
| Carbonic anhydrase 3 |
| Description
| Not Available |
| Synonyms
|
- CA-III
- Carbonate dehydratase III
- Carbonic anhydrase III
|
| Gene Name
| CA3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in carbonate dehydratase activity |
| Specific Function
| Reversible hydration of carbon dioxide.
|
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| response to oxidative stress |
| bicarbonate transport |
| one-carbon metabolic process |
| Cellular Component |
| cytosol |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| transition metal ion binding |
| zinc ion binding |
| lyase activity |
| carbon-oxygen lyase activity |
| hydro-lyase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| carbonate dehydratase activity |
| Molecular Function |
| zinc ion binding |
| carbonate dehydratase activity |
| nickel cation binding |
| Process |
| metabolic process |
| cellular metabolic process |
| one-carbon metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| 8q21.2 |
| SNPs
| CA3 |
| Gene Sequence
|
>783 bp
ATGGCCAAGGAGTGGGGCTACGCCAGTCACAACGGTCCTGACCACTGGCATGAACTTTTC
CCAAATGCCAAGGGGGAAAACCAGTCGCCCGTTGAGCTGCATACTAAAGACATCAGGCAT
GACCCTTCTCTGCAGCCATGGTCTGTGTCTTATGATGGTGGCTCTGCCAAGACCATCCTG
AATAATGGGAAGACCTGCCGAGTTGTATTTGATGATACTTATGATAGGTCAATGCTGAGA
GGGGGTCCTCTCCCTGGACCCTACCGACTTCGCCAGTTTCATCTTCACTGGGGCTCTTCG
GATGATCATGGCTCTGAGCACACCGTGGATGGAGTCAAGTATGCAGCGGAGCTTCATTTG
GTTCACTGGAACCCGAAGTATAACACTTTTAAAGAAGCCCTGAAGCAGCGCGATGGGATC
GCTGTGATTGGCATTTTTCTGAAGATAGGACATGAGAATGGCGAGTTCCAGATTTTCCTT
GATGCATTGGACAAGATTAAGACAAAGGGCAAGGAGGCGCCCTTCACAAAGTTTGACCCA
TCCTGCCTGTTCCCGGCATGCCGGGACTACTGGACCTACCAGGGCTCATTCACCACGCCG
CCCTGCGAGGAATGCATTGTGTGGCTGCTGCTGAAGGAGCCCATGACCGTGAGCTCTGAC
CAGATGGCCAAGCTGCGGAGCCTCCTCTCCAGTGCTGAGAACGAGCCCCCAGTGCCTCTT
GTGAGCAACTGGCGACCTCCACAGCCTATCAATAACAGGGTGGTGAGAGCTTCCTTCAAA
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 260 |
| Molecular Weight
| 29557.215 |
| Theoretical pI
| 7.338 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Carbonic anhydrase 3
MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL
VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP
SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL
VSNWRPPQPINNRVVRASFK
|
| External Links |
|---|
| GenBank ID Protein
| 4885099 |
| UniProtKB/Swiss-Prot ID
| P07451 |
| UniProtKB/Swiss-Prot Entry Name
| CAH3_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_005181.3 |
| GeneCard ID
| CA3 |
| GenAtlas ID
| CA3 |
| HGNC ID
| HGNC:1374 |
| References |
|---|
| General References
| Not Available |