Identification |
HMDB Protein ID
| CDBP01990 |
Secondary Accession Numbers
| Not Available |
Name
| cAMP-dependent protein kinase type I-alpha regulatory subunit |
Description
| Not Available |
Synonyms
|
- TSE1
- Tissue-specific extinguisher 1
|
Gene Name
| PRKAR1A |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in cAMP-dependent protein kinase regulator activity |
Specific Function
| Not Available |
GO Classification
|
Component |
protein complex |
camp-dependent protein kinase complex |
macromolecular complex |
Function |
enzyme regulator activity |
kinase regulator activity |
protein kinase regulator activity |
camp-dependent protein kinase regulator activity |
Process |
regulation of cellular protein metabolic process |
regulation of protein modification process |
regulation of protein amino acid phosphorylation |
biological regulation |
regulation of biological process |
regulation of metabolic process |
regulation of cellular process |
signal transduction |
regulation of cellular metabolic process |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Muscle/Heart Contraction | | Not Available | Acebutolol Action Pathway | | Not Available | Alprenolol Action Pathway | | Not Available | Atenolol Action Pathway | | Not Available | Betaxolol Action Pathway | | Not Available |
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 17q23-q24 |
SNPs
| PRKAR1A |
Gene Sequence
|
>1146 bp
ATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTC
TACGTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACT
GCTCGACCTGAGAGACCCATGGCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGGAG
GAGGCAAAACAGATTCAGAATCTGCAGAAAGCAGGCACTCGTACAGACTCAAGGGAGGAT
GAGATTTCTCCTCCTCCACCCAACCCAGTGGTTAAAGGTAGGAGGCGACGAGGTGCTATC
AGCGCTGAGGTCTACACGGAGGAAGATGCGGCATCCTATGTTAGAAAGGTTATACCAAAA
GATTACAAGACAATGGCCGCTTTAGCCAAAGCCATTGAAAAGAATGTGCTGTTTTCACAT
CTTGATGATAATGAGAGAAGTGATATTTTTGATGCCATGTTTTCGGTCTCCTTTATCGCA
GGAGAGACTGTGATTCAGCAAGGTGATGAAGGGGATAACTTCTATGTGATTGATCAAGGA
GAGACGGATGTCTATGTTAACAATGAATGGGCAACCAGTGTTGGGGAAGGAGGGAGCTTT
GGAGAACTTGCTTTGATTTATGGAACACCGAGAGCAGCCACTGTCAAAGCAAAGACAAAT
GTGAAATTGTGGGGCATCGACCGAGACAGCTATAGAAGAATCCTCATGGGAAGCACACTG
AGAAAGCGGAAGATGTATGAGGAATTCCTTAGTAAAGTCTCTATTTTAGAGTCTCTGGAC
AAGTGGGAACGTCTTACGGTAGCTGATGCATTGGAACCAGTGCAGTTTGAAGATGGGCAG
AAGATTGTGGTGCAGGGAGAACCAGGGGATGAGTTCTTCATTATTTTAGAGGGGTCAGCT
GCTGTGCTACAACGTCGGTCAGAAAATGAAGAGTTTGTTGAAGTGGGAAGATTGGGGCCT
TCTGATTATTTTGGTGAAATTGCACTACTGATGAATCGTCCTCGTGCTGCCACAGTTGTT
GCTCGTGGCCCCTTGAAGTGCGTTAAGCTGGACCGACCTAGATTTGAACGTGTTCTTGGC
CCATGCTCAGACATCCTCAAACGAAACATCCAGCAGTACAACAGTTTTGTGTCACTGTCT
GTCTGA
|
Protein Properties |
Number of Residues
| 381 |
Molecular Weight
| 42981.3 |
Theoretical pI
| 5.0 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>cAMP-dependent protein kinase type I-alpha regulatory subunit
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKE
EAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPK
DYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQG
ETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTL
RKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSA
AVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLG
PCSDILKRNIQQYNSFVSLSV
|
External Links |
GenBank ID Protein
| 179922 |
UniProtKB/Swiss-Prot ID
| P10644 |
UniProtKB/Swiss-Prot Entry Name
| KAP0_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| M18468 |
GeneCard ID
| PRKAR1A |
GenAtlas ID
| PRKAR1A |
HGNC ID
| HGNC:9388 |
References |
General References
| Not Available |