Showing Protein BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (CDBP01960)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01960
Secondary Accession Numbers Not Available
Name BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Description Not Available
Synonyms Not Available
Gene Name BNIP3
Protein Type Enzyme
Biological Properties
General Function Involved in positive regulation of apoptosis
Specific Function Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
envelope
organelle envelope
mitochondrial envelope
Process
regulation of apoptosis
positive regulation of apoptosis
regulation of cellular process
biological regulation
regulation of biological process
regulation of cell death
regulation of programmed cell death
Cellular Location
  1. Mitochondrion membrane
  2. Single-pass membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q26.3
SNPs BNIP3
Gene Sequence 
>585 bp
ATGTCGCAGAACGGAGCGCCCGGGATGCAGGAGGAGAGCCTGCAGGGCTCCTGGGTAGAA
CTGCACTTCAGCAATAATGGGAACGGGGGCAGCGTTCCAGCCTCGGTTTCTATTTATAAT
GGAGACATGGAAAAAATACTGCTGGACGCACAGCATGAGTCTGGACGGAGTAGCTCCAAG
AGCTCTCACTGTGACAGCCCACCTCGCTCGCAGACACCACAAGATACCAACAGGGCTTCT
GAAACAGATACCCATAGCATTGGAGAGAAAAACAGCTCACAGTCTGAGGAAGATGATATT
GAAAGAAGGAAAGAAGTTGAAAGCATCTTGAAGAAAAACTCAGATTGGATATGGGATTGG
TCAAGTCGGCCGGAAAATATTCCCCCCAAGGAGTTCCTCTTTAAACACCCGAAGCGCACG
GCCACCCTCAGCATGAGGAACACGAGCGTCATGAAGAAAGGGGGCATATTCTCTGCAGAA
TTTCTGAAAGTTTTCCTTCCATCTCTGCTGCTCTCTCATTTGCTGGCCATCGGATTGGGG
ATCTATATTGGAAGGCGTCTGACAACCTCCACCAGCACCTTTTGA
Protein Properties
Number of Residues 194
Molecular Weight 21540.8
Theoretical pI 6.8
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["164-184"]
Protein Sequence 
>BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
MSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDMEKILLDAQHESGRSSSK
SSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDW
SSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAEFLKVFLPSLLLSHLLAIGLG
IYIGRRLTTSTSTF
GenBank ID Protein 2511529
UniProtKB/Swiss-Prot ID Q12983
UniProtKB/Swiss-Prot Entry Name BNIP3_HUMAN
PDB IDs Not Available
GenBank Gene ID AF002697
GeneCard ID BNIP3
GenAtlas ID BNIP3
HGNC ID HGNC:1084
References
General References Not Available