| Identification |
|---|
| HMDB Protein ID
| CDBP01949 |
| Secondary Accession Numbers
| Not Available |
| Name
| Interleukin-5 precursor |
| Description
| Not Available |
| Synonyms
|
- B cell differentiation factor I
- Eosinophil differentiation factor
- IL-5
- T-cell replacing factor
- TRF
|
| Gene Name
| IL5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells |
| GO Classification
|
| Component |
| extracellular region |
| Function |
| cytokine activity |
| hematopoietin/interferon-class (d200-domain) cytokine receptor binding |
| signal transducer activity |
| receptor binding |
| growth factor activity |
| interleukin-5 receptor binding |
| Process |
| response to biotic stimulus |
| defense response |
| response to stimulus |
| immune response |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Fc Epsilon Receptor I Signaling in Mast Cells |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31.1 |
| SNPs
| IL5 |
| Gene Sequence
|
>405 bp
ATGAGGATGCTTCTGCATTTGAGTTTGCTAGCTCTTGGAGCTGCCTACGTGTATGCCATC
CCCACAGAAATTCCCACAAGTGCATTGGTGAAAGAGACCTTGGCACTGCTTTCTACTCAT
CGAACTCTGCTGATAGCCAATGAGACTCTGAGGATTCCTGTTCCTGTACATAAAAATCAC
CAACTGTGCACTGAAGAAATCTTTCAGGGAATAGGCACACTGGAGAGTCAAACTGTGCAA
GGGGGTACTGTGGAAAGACTATTCAAAAACTTGTCCTTAATAAAGAAATACATTGACGGC
CAAAAAAAAAAGTGTGGAGAAGAAAGACGGAGAGTAAACCAATTCCTAGACTACCTGCAA
GAGTTTCTTGGTGTAATGAACACCGAGTGGATAATAGAAAGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 134 |
| Molecular Weight
| 15238.0 |
| Theoretical pI
| 8.23 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Interleukin-5 precursor
MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNH
QLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQ
EFLGVMNTEWIIES
|
| External Links |
|---|
| GenBank ID Protein
| 33836 |
| UniProtKB/Swiss-Prot ID
| P05113 |
| UniProtKB/Swiss-Prot Entry Name
| IL5_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| X04688 |
| GeneCard ID
| IL5 |
| GenAtlas ID
| IL5 |
| HGNC ID
| HGNC:6016 |
| References |
|---|
| General References
| Not Available |