Identification
HMDB Protein ID CDBP01920
Secondary Accession Numbers Not Available
Name Heparin-binding growth factor 1
Description Not Available
Synonyms
  1. Acidic fibroblast growth factor
  2. Beta-endothelial cell growth factor
  3. ECGF-beta
  4. HBGF-1
  5. aFGF
Gene Name FGF1
Protein Type Enzyme
Biological Properties
General Function Involved in fibroblast growth factor receptor binding
Specific Function The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors
GO Classification
Function
binding
protein binding
receptor binding
growth factor activity
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs FGF1
Gene Sequence
>468 bp
ATGGCTGAAGGGGAAATCACCACCTTCACAGCCCTGACCGAGAAGTTTAATCTGCCTCCA
GGGAATTACAAGAAGCCCAAACTCCTCTACTGTAGCAACGGGGGCCACTTCCTGAGGATC
CTTCCGGATGGCACAGTGGATGGGACAAGGGACAGGAGCGACCAGCACATTCAGCTGCAG
CTCAGTGCGGAAAGCGTGGGGGAGGTGTATATAAAGAGTACCGAGACTGGCCAGTACTTG
GCCATGGACACCGACGGGCTTTTATACGGCTCACAGACACCAAATGAGGAATGTTTGTTC
CTGGAAAGGCTGGAGGAGAACCATTACAACACCTATATATCCAAGAAGCATGCAGAGAAG
AATTGGTTTGTTGGCCTCAAGAAGAATGGGAGCTGCAAACGCGGTCCTCGGACTCACTAT
GGCCAGAAAGCAATCTTGTTTCTCCCCCTGCCAGTCTCTTCTGATTAA
Protein Properties
Number of Residues 155
Molecular Weight 17459.6
Theoretical pI 7.04
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Heparin-binding growth factor 1
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ
LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK
NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
GenBank ID Protein 4503697
UniProtKB/Swiss-Prot ID P05230
UniProtKB/Swiss-Prot Entry Name FGF1_HUMAN
PDB IDs
GenBank Gene ID NM_000800.3
GeneCard ID FGF1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available