Identification |
HMDB Protein ID
| CDBP01920 |
Secondary Accession Numbers
| Not Available |
Name
| Heparin-binding growth factor 1 |
Description
| Not Available |
Synonyms
|
- Acidic fibroblast growth factor
- Beta-endothelial cell growth factor
- ECGF-beta
- HBGF-1
- aFGF
|
Gene Name
| FGF1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in fibroblast growth factor receptor binding |
Specific Function
| The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors |
GO Classification
|
Function |
binding |
protein binding |
receptor binding |
growth factor activity |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q31 |
SNPs
| FGF1 |
Gene Sequence
|
>468 bp
ATGGCTGAAGGGGAAATCACCACCTTCACAGCCCTGACCGAGAAGTTTAATCTGCCTCCA
GGGAATTACAAGAAGCCCAAACTCCTCTACTGTAGCAACGGGGGCCACTTCCTGAGGATC
CTTCCGGATGGCACAGTGGATGGGACAAGGGACAGGAGCGACCAGCACATTCAGCTGCAG
CTCAGTGCGGAAAGCGTGGGGGAGGTGTATATAAAGAGTACCGAGACTGGCCAGTACTTG
GCCATGGACACCGACGGGCTTTTATACGGCTCACAGACACCAAATGAGGAATGTTTGTTC
CTGGAAAGGCTGGAGGAGAACCATTACAACACCTATATATCCAAGAAGCATGCAGAGAAG
AATTGGTTTGTTGGCCTCAAGAAGAATGGGAGCTGCAAACGCGGTCCTCGGACTCACTAT
GGCCAGAAAGCAATCTTGTTTCTCCCCCTGCCAGTCTCTTCTGATTAA
|
Protein Properties |
Number of Residues
| 155 |
Molecular Weight
| 17459.6 |
Theoretical pI
| 7.04 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Heparin-binding growth factor 1
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ
LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK
NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
|
External Links |
GenBank ID Protein
| 4503697 |
UniProtKB/Swiss-Prot ID
| P05230 |
UniProtKB/Swiss-Prot Entry Name
| FGF1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| NM_000800.3 |
GeneCard ID
| FGF1 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |