| Identification |
|---|
| HMDB Protein ID
| CDBP01893 |
| Secondary Accession Numbers
| Not Available |
| Name
| P3 protein |
| Description
| Not Available |
| Synonyms
|
- Solute carrier family 10 member 3
|
| Gene Name
| SLC10A3 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in bile acid:sodium symporter activity |
| Specific Function
| The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions |
| GO Classification
|
| Component |
| membrane |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| organic acid transmembrane transporter activity |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| organic acid:sodium symporter activity |
| transporter activity |
| bile acid:sodium symporter activity |
| Process |
| sodium ion transport |
| establishment of localization |
| transport |
| organic anion transport |
| anion transport |
| monovalent inorganic cation transport |
| ion transport |
| cation transport |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| SLC10A3 |
| Gene Sequence
|
>1434 bp
ATGGTGTTAATGCAGGACAAGGGCAGCTCTCAGCAGTGGCCTGGTCTGGGGGGCGAGGGT
GGTGGCACAGGTCCCTTAAGCATGCTCAGAGCTGCCCTGCTGCTCATCAGCCTGCCATGG
GGGGCCCAAGGGACAGCCAGCACCAGCCTCAGCACTGCTGGGGGTCACACCGTGCCACCG
ACTGGGGGCCGCTACTTGAGCATTGGAGATGGCTCTGTGATGGAGTTTGAGTTTCCTGAG
GACAGTGAGGGCATCATCGTGATCTCCAGCCAGTACCCAGGCCAGGCCAACAGGACGGCG
CCTGGCCCCATGCTCAGGGTCACCTCCCTGGACACAGAGGTGCTGACCATCAAGAACGTG
AGTGCTATAACCTGGGGAGGCGGGGGTGGCTTTGTGGTGAGCATCCACTCAGGCCTGGCT
GGGCTGGCCCCACTCCACATCCAGCTCGTGGACGCCCATGAGGCCCCGCCCACACTGATT
GAGGAGCGGAGAGACTTCTGCATCAAGGTCTCACCTGCTGAAGACACGCCTGCCACCCTC
AGCGCCGACCTGGCCCACTTCTCGGAAAACCCAATCCTCTACCTGCTCCTGCCTCTTATC
TTTGTCAACAAGTGTTCGTTTGGGTGCAAAGTGGAACTCGAGGTTCTGAAGGGGCTCATG
CAGAGCCCCCAGCCCATGCTGCTGGGCCTCCTGGGCCAGTTTCTGGTCATGCCCTTGTAC
GCTTTCCTCATGGCCAAGGTCTTCATGCTGCCCAAGGCCCTGGCTCTGGGCCTCATCATC
ACCTGCTCGTCGCCTGGCGGCGGGGGGAGCTACCTCTTCAGCCTCCTTCTTGGAGGGGAC
GTCACCCTGGCCATCTCCATGACTTTCCTCTCTACGGTGGCTGCCACTGGCTTCTTGCCT
CTGTCTTCGGCCATCTACAGCCGCCTGCTCAGCATCCATGAGACGCTCCACGTGCCCATC
TCCAAGATCCTGGGGACCCTGCTGTTCATTGCCATCCCCATAGCCGTGGGCGTGCTGATC
AAGTCCAAGCTCCCCAAGTTCTCCCAGCTGCTGCTGCAGGTCGTCAAGCCCTTCAGCTTT
GTGCTCCTCCTGGGCGGCCTCTTCCTGGCCTATCGCATGGGGGTCTTCATCCTGGCAGGC
ATCCGGCTACCCATCGTACTGGTGGGTATCACGGTGCCCCTGGTTGGCCTGTTGGTGGGC
TACTGCCTAGCCACGTGTCTGAAGCTGCCAGTGGCCCAGCGGCGGACGGTCAGCATTGAG
GTAGGGGTGCAGAACAGCCTGCTGGCCTTGGCCATGCTGCAGCTATCCCTCCGCCGCCTT
CAAGCTGACTATGCCTCCCAGGCCCCCTTCATTGTGGCGCTGAGCGGCACCTCCGAGATG
CTGGCCTTGGTCATTGGCCACTTCATCTACAGCAGCCTGTTCCCAGTTCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 477 |
| Molecular Weight
| 50332.2 |
| Theoretical pI
| 7.86 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["225-245", "253-273", "281-301", "320-340", "361-381", "383-403", "417-437", "450-470"]
|
| Protein Sequence
|
>P3 protein
MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
|
| External Links |
|---|
| GenBank ID Protein
| 150171072 |
| UniProtKB/Swiss-Prot ID
| P09131 |
| UniProtKB/Swiss-Prot Entry Name
| P3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BX664739 |
| GeneCard ID
| SLC10A3 |
| GenAtlas ID
| SLC10A3 |
| HGNC ID
| HGNC:22979 |
| References |
|---|
| General References
| Not Available |