| Identification |
|---|
| HMDB Protein ID
| CDBP01882 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mitochondrial ornithine transporter 1 |
| Description
| Not Available |
| Synonyms
|
- Solute carrier family 25 member 15
|
| Gene Name
| SLC25A15 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transporter activity |
| Specific Function
| Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
|
| GO Classification
|
| Biological Process |
| mitochondrial ornithine transport |
| cellular amino acid metabolic process |
| urea cycle |
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| binding |
| transporter activity |
| Molecular Function |
| L-ornithine transmembrane transporter activity |
| Process |
| transport |
| transmembrane transport |
| establishment of localization |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Arginine and Proline Metabolism |    |  | | Prolidase Deficiency (PD) |    | Not Available | | Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency) |    | Not Available | | Hyperprolinemia Type II |    | Not Available | | Hyperprolinemia Type I |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 13 |
| Locus
| 13q14 |
| SNPs
| SLC25A15 |
| Gene Sequence
|
>906 bp
ATGAAATCCAATCCTGCTATCCAGGCTGCCATTGACCTCACAGCGGGGGCTGCAGGAGGT
ACAGCATGTGTACTGACCGGGCAGCCCTTTGACACAATGAAAGTGAAGATGCAGACGTTC
CCTGACCTGTACCGGGGCCTCACCGACTGCTGCCTGAAGACTTACTCCCAGGTGGGCTTC
CGTGGCTTCTACAAGGGTACCAGTCCAGCACTAATCGCCAACATCGCTGAGAACTCAGTC
CTCTTCATGTGCTACGGCTTCTGCCAGCAGGTGGTGCGGAAAGTGGCTGGATTGGACAAG
CAGGCAAAGCTGAGTGATCTGCAGAATGCAGCCGCCGGTTCCTTCGCCTCTGCCTTTGCT
GCACTGGTGCTCTGCCCCACGGAGCTCGTGAAGTGCCGGCTGCAGACCATGTATGAGATG
GAGACATCAGGGAAGATAGCCAAGAGCCAGAATACAGTGTGGTCTGTCATCAAAAGTATT
CTTAGGAAAGATGGCCCCTTGGGGTTCTACCATGGACTCTCAAGCACTTTACTTCGAGAA
GTACCAGGCTATTTCTTCTTCTTCGGTGGCTATGAACTGAGCCGGTCCTTTTTTGCATCA
GGGAGATCAAAAGATGAATTAGGCCCTGTACCTTTGATGTTAAGTGGTGGAGTTGGTGGG
ATTTGCCTCTGGCTTGCGGTATACCCAGTGGATTGTATCAAATCCAGAATTCAAGTTCTT
TCCATGTCTGGAAAACAGGCAGGATTTATCAGAACCTTTATAAATGTTGTGAAAAATGAA
GGAATAACGGCCTTATATTCTGGACTGAAACCTACTATGATTCGAGCATTCCCTGCCAAT
GGAGCACTCTTTTTGGCCTACGAATATAGCAGGAAGTTGATGATGAACCAGTTGGAAGCA
TACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 301 |
| Molecular Weight
| 32735.96 |
| Theoretical pI
| 9.126 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Mitochondrial ornithine transporter 1
MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGF
RGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFA
ALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLRE
VPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVL
SMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEA
Y
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9Y619 |
| UniProtKB/Swiss-Prot Entry Name
| ORNT1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF112968 |
| GeneCard ID
| SLC25A15 |
| GenAtlas ID
| SLC25A15 |
| HGNC ID
| HGNC:10985 |
| References |
|---|
| General References
| Not Available |