| Identification |
|---|
| HMDB Protein ID
| CDBP01868 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cytochrome b-c1 complex subunit 8 |
| Description
| Not Available |
| Synonyms
|
- Complex III subunit 8
- Complex III subunit VIII
- Ubiquinol-cytochrome c reductase complex 9.5 kDa protein
- Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
|
| Gene Name
| UQCRQ |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ubiquinol-cytochrome-c reductase activity |
| Specific Function
| This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone |
| GO Classification
|
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| cation transmembrane transporter activity |
| inorganic cation transmembrane transporter activity |
| monovalent inorganic cation transmembrane transporter activity |
| hydrogen ion transmembrane transporter activity |
| ubiquinol-cytochrome-c reductase activity |
| transporter activity |
|
| Cellular Location
|
- Mitochondrion inner membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31.1 |
| SNPs
| UQCRQ |
| Gene Sequence
|
>249 bp
ATGGGCCGCGAGTTTGGGAATCTGACGCGGATGCGGCATGTGATCAGCTACAGCTTGTCA
CCGTTCGAGCAGCGCGCCTATCCGCACGTCTTCACTAAAGGAATCCCCAATGTTCTGCGC
CGCATTCGGGAGTCTTTCTTTCGCGTGGTGCCGCAGTTTGTAGTGTTTTATCTTATCTAC
ACATGGGGGACTGAAGAGTTCGAGAGATCCAAGAGGAAGAATCCAGCTGCCTATGAAAAT
GACAAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 82 |
| Molecular Weight
| 9906.3 |
| Theoretical pI
| 10.5 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cytochrome b-c1 complex subunit 8
MGREFGNLTRMRHVISYSLSPFEQRAYPHVFTKGIPNVLRRIRESFFRVVPQFVVFYLIY
TWGTEEFERSKRKNPAAYENDK
|
| External Links |
|---|
| GenBank ID Protein
| 12655079 |
| UniProtKB/Swiss-Prot ID
| O14949 |
| UniProtKB/Swiss-Prot Entry Name
| QCR8_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC001390 |
| GeneCard ID
| UQCRQ |
| GenAtlas ID
| UQCRQ |
| HGNC ID
| HGNC:29594 |
| References |
|---|
| General References
| Not Available |