Identification |
HMDB Protein ID
| CDBP01851 |
Secondary Accession Numbers
| Not Available |
Name
| Calcium-binding protein p22 |
Description
| Not Available |
Synonyms
|
- Calcineurin B homolog
- Calcineurin homologous protein
- Calcium-binding protein CHP
|
Gene Name
| CHP |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in calcium ion binding |
Specific Function
| Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1 |
GO Classification
|
Function |
ion binding |
cation binding |
metal ion binding |
binding |
calcium ion binding |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 15q13.3 |
SNPs
| CHP |
Gene Sequence
|
>588 bp
ATGGGTTCTCGGGCCTCCACGTTACTGCGGGACGAAGAGCTCGAGGAGATCAAGAAGGAG
ACCGGCTTTTCCCACAGTCAAATCACTCGCCTCTACAGCCGGTTCACCAGCCTGGACAAA
GGAGAGAATGGGACTCTCAGCCGGGAAGATTTCCAGAGGATTCCAGAACTTGCCATCAAC
CCACTGGGGGACCGGATCATCAATGCCTTCTTTCCAGAGGGAGAGGACCAGGTAAACTTC
CGTGGATTCATGCGAACTTTGGCTCATTTCCGCCCCATTGAGGATAATGAAAAGAGCAAA
GATGTGAATGGACCCGAACCACTCAACAGCCGAAGCAACAAACTGCACTTTGCTTTTCGA
CTATATGATTTGGATAAAGATGAAAAGATCTCCCGTGATGAGCTGTTACAGGTGCTACGC
ATGATGGTCGGAGTAAATATCTCAGATGAGCAGCTGGGCAGCATCGCAGACAGGACCATT
CAGGAGGCTGATCAGGATGGGGACAGTGCCATATCTTTCACAGAATTTGTTAAGGTTTTG
GAGAAGGTGGATGTAGAACAGAAAATGAGCATCCGATTTCTTCACTAA
|
Protein Properties |
Number of Residues
| 195 |
Molecular Weight
| 22456.0 |
Theoretical pI
| 4.73 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Calcium-binding protein p22
MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN
PLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFR
LYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL
EKVDVEQKMSIRFLH
|
External Links |
GenBank ID Protein
| 189069138 |
UniProtKB/Swiss-Prot ID
| Q99653 |
UniProtKB/Swiss-Prot Entry Name
| CHP1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK312582 |
GeneCard ID
| CHP |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |