1849

CDBP01848

Transient receptor potential cation channel subfamily V member 1

Q8NER1

TRPV1_HUMAN

false true

Receptor

Homo_sapiens

TRPV1

839

94955.3

7.26

Involved in ion channel activity

Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. May be involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL

["None"]

["434-454", "477-497", "514-534", "536-556", "580-600", "660-680"]

AJ277028

8977866

TRPV1

Chromosome:1

17p13.2

TRPV1

HGNC:12716

true

2020-06-12T23:07:00Z

2020-07-28T02:27:17Z