Showing Protein Mitochondrial-processing peptidase subunit alpha (CDBP01838)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP01838
Secondary Accession Numbers Not Available
Name Mitochondrial-processing peptidase subunit alpha
Description Not Available
Synonyms
  1. Alpha-MPP
  2. P-55
Gene Name PMPCA
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Cleaves presequences (transit peptides) from mitochondrial protein precursors
GO Classification
Function
catalytic activity
hydrolase activity
transition metal ion binding
zinc ion binding
metalloendopeptidase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
endopeptidase activity
ion binding
cation binding
metal ion binding
binding
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis
Cellular Location
  1. Mitochondrion matrix
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9q34.3
SNPs PMPCA
Gene Sequence 
>1578 bp
ATGGCGGCTGTGGTGCTGGCGGCGACGCGGTTGCTGCGGGGCTCGGGTTCTTGGGGCTGT
TCGCGGCTGAGGTTTGGACCTCCTGCGTACAGACGGTTTAGTAGTGGTGGTGCCTATCCC
AACATCCCCCTCTCTTCTCCCTTACCTGGAGTACCCAAGCCTGTTTTTGCTACAGTTGAT
GGACAGGAAAAGTTTGAAACCAAAGTAACCACATTGGATAATGGGCTTCGCGTGGCATCT
CAGAATAAGTTTGGACAGTTTTGTACAGTAGGAATTCTTATCAATTCAGGATCGAGATAT
GAAGCGAAATACCTTAGTGGAATTGCTCACTTTTTGGAAAAATTGGCATTTTCGTCTACT
GCTCGATTTGACAGCAAAGATGAAATTCTGCTTACGTTGGAAAAGCATGGGGGTATCTGT
GACTGCCAGACATCAAGAGACACCACCATGTATGCTGTGTCTGCTGATAGCAAAGGCTTG
GACACGGTGGTTGCCTTACTGGCTGATGTGGTTCTGCAGCCCCGGCTAACAGATGAAGAA
GTCGAGATGACGCGGATGGCGGTCCAGTTTGAGCTGGAGGACCTGAACCTGCGGCCTGAC
CCAGAGCCACTTCTCACCGAGATGATTCATGAAGCGGCTTACAGGGAGAACACAGTTGGC
CTCCACCGTTTCTGCCCCACAGAAAACGTAGCAAAGATCAACCGAGAGGTGCTGCATTCC
TACCTGAGGAACTACTACACTCCCGACCGCATGGTGCTGGCCGGCGTGGGCGTGGAGCAC
GAGCATCTGGTGGACTGTGCCCGGAAGTACCTCCTGGGGGTCCAGCCGGCCTGGGGGAGC
GCAGAGGCCGTGGATATTGACAGATCTGTGGCCCAGTACACTGGGGGGATTGCCAAGCTA
GAAAGAGACATGTCCAATGTCAGCCTGGGCCCGACCCCCATCCCCGAGCTCACGCACATC
ATGGTTGGACTGGAGAGCTGCTCCTTCCTGGAGGAGGACTTCATCCCCTTTGCAGTGTTG
AACATGATGATGGGCGGAGGTGGCTCCTTCTCGGCTGGTGGGCCCGGCAAGGGCATGTTC
TCCAGGCTCTACCTCAACGTGCTCAACAGGCACCACTGGATGTATAACGCGACCTCCTAC
CACCACAGCTACGAGGACACTGGCCTCCTTTGCATCCATGCCAGCGCCGACCCAAGACAG
GTTCGAGAAATGGTAGAAATCATCACAAAGGAGTTTATTTTAATGGGCGGAACCGTGGAC
ACGGTGGAGCTGGAACGAGCCAAGACGCAGCTGACATCAATGCTCATGATGAACCTGGAA
TCCAGGCCTGTGATCTTCGAGGATGTGGGGAGGCAGGTGCTGGCCACTCGCTCCAGAAAG
CTGCCGCACGAGCTGTGCACGCTCATCCGCAACGTGAAGCCGGAAGATGTGAAGAGAGTC
GCTTCTAAGATGCTCCGAGGGAAGCCGGCAGTGGCCGCCCTGGGTGACCTGACTGACCTG
CCCACGTATGAGCACATCCAGACCGCCCTGTCGAGTAAGGACGGGCGCCTGCCCAGGACG
TACCGGCTCTTCCGGTAG
Protein Properties
Number of Residues 525
Molecular Weight 58252.4
Theoretical pI 6.91
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Mitochondrial-processing peptidase subunit alpha
MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVD
GQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSST
ARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEE
VEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHS
YLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKL
ERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMF
SRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVD
TVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRV
ASKMLRGKPAVAALGDLTDLPTYEHIQTALSSKDGRLPRTYRLFR
GenBank ID Protein 24308013
UniProtKB/Swiss-Prot ID Q10713
UniProtKB/Swiss-Prot Entry Name MPPA_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_015160.1
GeneCard ID PMPCA
GenAtlas ID PMPCA
HGNC ID HGNC:18667
References
General References Not Available