Identification
HMDB Protein ID CDBP01811
Secondary Accession Numbers Not Available
Name Pleiotrophin
Description Not Available
Synonyms
  1. HB-GAM
  2. HBBM
  3. HBGF-8
  4. HBNF-1
  5. Heparin-binding brain mitogen
  6. Heparin-binding growth factor 8
  7. Heparin-binding growth-associated molecule
  8. Heparin-binding neurite outgrowth-promoting factor 1
  9. OSF-1
  10. Osteoblast-specific factor 1
  11. PTN
Gene Name PTN
Protein Type Enzyme
Biological Properties
General Function Involved in growth factor activity
Specific Function Heparin binding mitogenic protein. Has neurite extension activity
GO Classification
Function
binding
protein binding
receptor binding
growth factor activity
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:7
Locus 7q33
SNPs PTN
Gene Sequence
>507 bp
ATGCAGGCTCAACAGTACCAGCAGCAGCGTCGAAAATTTGCAGCTGCCTTCTTGGCATTC
ATTTTCATACTGGCAGCTGTGGATACTGCTGAAGCAGGGAAGAAAGAGAAACCAGAAAAA
AAAGTGAAGAAGTCTGACTGTGGAGAATGGCAGTGGAGTGTGTGTGTGCCCACCAGTGGA
GACTGTGGGCTGGGCACACGGGAGGGCACTCGGACTGGAGCTGAGTGCAAGCAAACCATG
AAGACCCAGAGATGTAAGATCCCCTGCAACTGGAAGAAGCAATTTGGCGCGGAGTGCAAA
TACCAGTTCCAGGCCTGGGGAGAATGTGACCTGAACACAGCCCTGAAGACCAGAACTGGA
AGTCTGAAGCGAGCCCTGCACAATGCCGAATGCCAGAAGACTGTCACCATCTCCAAGCCC
TGTGGCAAACTGACCAAGCCCAAACCTCAAGCAGAATCTAAGAAGAAGAAAAAGGAAGGC
AAGAAACAGGAGAAGATGCTGGATTAA
Protein Properties
Number of Residues 168
Molecular Weight 18941.9
Theoretical pI 10.3
Pfam Domain Function
Signals
  • ["1-32"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Pleiotrophin
MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
GenBank ID Protein 2564040
UniProtKB/Swiss-Prot ID P21246
UniProtKB/Swiss-Prot Entry Name PTN_HUMAN
PDB IDs Not Available
GenBank Gene ID AB004306
GeneCard ID PTN
GenAtlas ID PTN
HGNC ID HGNC:9630
References
General References Not Available