Showing Protein Natriuretic peptides B (CDBP01805)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01805
Secondary Accession Numbers Not Available
Name Natriuretic peptides B
Description Not Available
Synonyms
  1. BNP(1-28)
  2. BNP(1-29)
  3. BNP(1-30)
  4. BNP(1-32)
  5. BNP(2-31)
  6. BNP(3-29)
  7. BNP(3-30)
  8. BNP(3-32)
  9. BNP(4-27)
  10. BNP(4-29)
  11. BNP(4-30)
  12. BNP(4-31)
  13. BNP(4-32)
  14. BNP(5-29)
  15. BNP(5-31)
  16. BNP(5-32)
  17. BNP-32
  18. Brain natriuretic peptide 32
  19. Gamma-brain natriuretic peptide
Gene Name NPPB
Protein Type Enzyme
Biological Properties
General Function Involved in hormone activity
Specific Function Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3
GO Classification
Component
extracellular region
Function
hormone activity
binding
protein binding
receptor binding
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs NPPB
Gene Sequence 
>405 bp
ATGGATCCCCAGACAGCACCTTCCCGGGCGCTCCTGCTCCTGCTCTTCTTGCATCTGGCT
TTCCTGGGAGGTCGTTCCCACCCGCTGGGCAGCCCCGGTTCAGCCTCGGACTTGGAAACG
TCCGGGTTACAGGAGCAGCGCAACCATTTGCAGGGCAAACTGTCGGAGCTGCAGGTGGAG
CAGACATCCCTGGAGCCCCTCCAGGAGAGCCCCCGTCCCACAGGTGTCTGGAAGTCCCGG
GAGGTAGCCACCGAGGGCATCCGTGGGCACCGCAAAATGGTCCTCTACACCCTGCGGGCA
CCACGAAGCCCCAAGATGGTGCAAGGGTCTGGCTGCTTTGGGAGGAAGATGGACCGGATC
AGCTCCTCCAGTGGCCTGGGCTGCAAAGTGCTGAGGCGGCATTAA
Protein Properties
Number of Residues 134
Molecular Weight 14725.8
Theoretical pI 11.01
Pfam Domain Function
Signals
  • ["1-26"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Natriuretic peptides B
MDPQTAPSRALLLLLFLHLAFLGGRSHPLGSPGSASDLETSGLQEQRNHLQGKLSELQVE
QTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRI
SSSSGLGCKVLRRH
GenBank ID Protein 3171894
UniProtKB/Swiss-Prot ID P16860
UniProtKB/Swiss-Prot Entry Name ANFB_HUMAN
PDB IDs Not Available
GenBank Gene ID AL021155
GeneCard ID NPPB
GenAtlas ID NPPB
HGNC ID HGNC:7940
References
General References Not Available