Cannabis Compound Database: Showing Protein Solute carrier family 2, facilitated glucose transporter member 1 (CDBP01794)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP01794

Secondary Accession Numbers

Not Available

Name

Solute carrier family 2, facilitated glucose transporter member 1

Description

Not Available

Synonyms

GLUT-1
Glucose transporter type 1, erythrocyte/brain
HepG2 glucose transporter

Gene Name

SLC2A1

Protein Type

Enzyme

Biological Properties

General Function

Involved in glucose transmembrane transporter activity

Specific Function

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.

GO Classification

Biological Process
cellular response to glucose starvation
L-ascorbic acid metabolic process
energy reserve metabolic process
regulation of insulin secretion
response to osmotic stress
Cellular Component
plasma membrane
cell-cell junction
female pronucleus
basolateral plasma membrane
melanosome
caveola
midbody
integral to membrane
Component
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
monosaccharide transmembrane transporter activity
hexose transmembrane transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
transporter activity
glucose transmembrane transporter activity
carbohydrate transmembrane transporter activity
sugar transmembrane transporter activity
Molecular Function
glucose transmembrane transporter activity
D-glucose transmembrane transporter activity
dehydroascorbic acid transporter activity
xenobiotic transporter activity
Process
establishment of localization
transport
transmembrane transport

Cellular Location

Cell membrane
Melanosome
Multi-pass membrane protein

Pathways

Name	SMPDB/Pathwhiz	KEGG
Lactose Synthesis		Not Available
HIF-1 signaling pathway	Not Available
Insulin secretion	Not Available
Adipocytokine signaling pathway	Not Available
Bile secretion	Not Available

Gene Properties

Chromosome Location

Locus

1p34.2

SNPs

SLC2A1

Gene Sequence

>1479 bp
ATGGAGCCCAGCAGCAAGAAGCTGACGGGTCGCCTCATGCTGGCCGTGGGAGGAGCAGTG
CTTGGCTCCCTGCAGTTTGGCTACAACACTGGAGTCATCAATGCCCCCCAGAAGGTGATC
GAGGAGTTCTACAACCAGACATGGGTCCACCGCTATGGGGAGAGCATCCTGCCCACCACG
CTCACCACGCTCTGGTCCCTCTCAGTGGCCATCTTTTCTGTTGGGGGCATGATTGGCTCC
TTCTCTGTGGGCCTTTTCGTTAACCGCTTTGGCCGGCGGAATTCAATGCTGATGATGAAC
CTGCTGGCCTTCGTGTCCGCCGTGCTCATGGGCTTCTCGAAACTGGGCAAGTCCTTTGAG
ATGCTGATCCTGGGCCGCTTCATCATCGGTGTGTACTGCGGCCTGACCACAGGCTTCGTG
CCCATGTATGTGGGTGAAGTGTCACCCACAGCCCTTCGTGGGGCCCTGGGCACCCTGCAC
CAGCTGGGCATCGTCGTCGGCATCCTCATCGCCCAGGTGTTCGGCCTGGACTCCATCATG
GGCAACAAGGACCTGTGGCCCCTGCTGCTGAGCATCATCTTCATCCCGGCCCTGCTGCAG
TGCATCGTGCTGCCCTTCTGCCCCGAGAGTCCCCGCTTCCTGCTCATCAACCGCAACGAG
GAGAACCGGGCCAAGAGTGTGCTAAAGAAGCTGCGCGGGACAGCTGACGTGACCCATGAC
CTGCAGGAGATGAAGGAAGAGAGTCGGCAGATGATGCGGGAGAAGAAGGTCACCATCCTG
GAGCTGTTCCGCTCCCCCGCCTACCGCCAGCCCATCCTCATCGCTGTGGTGCTGCAGCTG
TCCCAGCAGCTGTCTGGCATCAACGCTGTCTTCTATTACTCCACGAGCATCTTCGAGAAG
GCGGGGGTGCAGCAGCCTGTGTATGCCACCATTGGCTCCGGTATCGTCAACACGGCCTTC
ACTGTCGTGTCGCTGTTTGTGGTGGAGCGAGCAGGCCGGCGGACCCTGCACCTCATAGGC
CTCGCTGGCATGGCGGGTTGTGCCATACTCATGACCATCGCGCTAGCACTGCTGGAGCAG
CTACCCTGGATGTCCTATCTGAGCATCGTGGCCATCTTTGGCTTTGTGGCCTTCTTTGAA
GTGGGTCCTGGCCCCATCCCATGGTTCATCGTGGCTGAACTCTTCAGCCAGGGTCCACGT
CCAGCTGCCATTGCCGTTGCAGGCTTCTCCAACTGGACCTCAAATTTCATTGTGGGCATG
TGCTTCCAGTATGTGGAGCAACTGTGTGGTCCCTACGTCTTCATCATCTTCACTGTGCTC
CTGGTTCTGTTCTTCATCTTCACCTACTTCAAAGTTCCTGAGACTAAAGGCCGGACCTTC
GATGAGATCGCTTCCGGCTTCCGGCAGGGGGGAGCCAGCCAAAGTGACAAGACACCCGAG
GAGCTGTTCCATCCCCTGGGGGCTGATTCCCAAGTGTGA

Protein Properties

Number of Residues

492

Molecular Weight

54083.325

Theoretical pI

8.719

Pfam Domain Function

Sugar_tr (PF00083 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Solute carrier family 2, facilitated glucose transporter member 1
MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV

External Links

GenBank ID Protein

166795299

UniProtKB/Swiss-Prot ID

P11166

UniProtKB/Swiss-Prot Entry Name

GTR1_HUMAN

PDB IDs