Identification
HMDB Protein ID CDBP01793
Secondary Accession Numbers Not Available
Name Adrenodoxin, mitochondrial precursor
Description Not Available
Synonyms
  1. Adrenal ferredoxin
  2. Ferredoxin- 1
  3. Hepatoredoxin
Gene Name FDX1
Protein Type Enzyme
Biological Properties
General Function Energy production and conversion
Specific Function Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450
GO Classification
Function
binding
transition metal ion binding
electron transporter activity
iron ion binding
transporter activity
ion binding
cation binding
Process
cellular metabolism
electron transport
generation of precursor metabolites and energy
physiological process
metabolism
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:11
Locus 11q22
SNPs FDX1
Gene Sequence
>555 bp
ATGGCTGCCGCTGGGGGCGCCCGGCTGCTGCGCGCCGCTTCTGCTGTCCTCGGCGGCCCG
GCCGGCCGGTGGCTGCACCACGCTGGGTCCCGCGCTGGATCCAGCGGCCTGCTGAGGAAC
CGGGGGCCGGGCGGTAGCGCGGAGGCGAGCCGGTCGCTGAGCGTGTCGGCGCGGGCCCGG
AGCAGCTCAGAAGATAAAATAACAGTCCACTTTATAAACCGTGATGGTGAAACATTAACA
ACCAAAGGAAAAGTTGGTGATTCTCTGCTAGATGTTGTGGTTGAAAATAATCTAGATATT
GATGGCTTTGGTGCATGTGAGGGAACCCTGGCTTGTTCAACCTGTCACCTCATCTTTGAA
GATCACATATATGAGAAGTTAGATGCAATCACTGATGAGGAGAATGACATGCTCGATCTG
GCATATGGACTAACAGACAGATCACGGTTGGGCTGCCAAATCTGTTTGACAAAATCTATG
GACAATATGACTGTTCGAGTGCCTGAAACAGTGGCTGATGCCAGACAATCCATTGATGTG
GGCAAGACCTCCTGA
Protein Properties
Number of Residues 184
Molecular Weight 19393.0
Theoretical pI 5.62
Pfam Domain Function
Signals
  • ["1-15"]
Transmembrane Regions Not Available
Protein Sequence
>Adrenodoxin, mitochondrial precursor
MAAAGGARLLRAASAVLGGPAGRWLHHAGSRAGSSGLLRNRGPGGSAEASRSLSVSARAR
SSSEDKITVHFINRDGETLTTKGKVGDSLLDVVVENNLDIDGFGACEGTLACSTCHLIFE
DHIYEKLDAITDEENDMLDLAYGLTDRSRLGCQICLTKSMDNMTVRVPETVADARQSIDV
GKTS
GenBank ID Protein 557734
UniProtKB/Swiss-Prot ID P10109
UniProtKB/Swiss-Prot Entry Name ADX_HUMAN
PDB IDs Not Available
GenBank Gene ID M23668
GeneCard ID FDX1
GenAtlas ID FDX1
HGNC ID HGNC:3638
References
General References Not Available