| Identification |
|---|
| HMDB Protein ID
| CDBP01789 |
| Secondary Accession Numbers
| Not Available |
| Name
| Annexin A5 |
| Description
| Not Available |
| Synonyms
|
- Anchorin CII
- Annexin V
- Annexin-5
- CBP-I
- Calphobindin I
- Endonexin II
- Lipocortin V
- PAP-I
- PP4
- Placental anticoagulant protein 4
- Placental anticoagulant protein I
- Thromboplastin inhibitor
- VAC-alpha
- Vascular anticoagulant-alpha
|
| Gene Name
| ANXA5 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade |
| GO Classification
|
| Function |
| metal ion binding |
| binding |
| calcium-dependent phospholipid binding |
| calcium ion binding |
| lipid binding |
| phospholipid binding |
| ion binding |
| cation binding |
| Process |
| regulation of coagulation |
| negative regulation of coagulation |
| biological regulation |
| regulation of biological process |
| regulation of multicellular organismal process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q26-q28|4q27 |
| SNPs
| ANXA5 |
| Gene Sequence
|
>963 bp
ATGGCACAGGTTCTCAGAGGCACTGTGACTGACTTCCCTGGATTTGATGAGCGGGCTGAT
GCAGAAACTCTTCGGAAGGCTATGAAAGGCTTGGGCACAGATGAGGAGAGCATCCTGACT
CTGTTGACATCCCGAAGTAATGCTCAGCGCCAGGAAATCTCTGCAGCTTTTAAGACTCTG
TTTGGCAGGGATCTTCTGGATGACCTGAAATCAGAACTAACTGGAAAATTTGAAAAATTA
ATTGTGGCTCTGATGAAACCCTCTCGGCTTTATGATGCTTATGAACTGAAACATGCCTTG
AAGGGAGCTGGAACAAATGAAAAAGTACTGACAGAAATTATTGCTTCAAGGACACCTGAA
GAACTGAGAGCCATCAAACAAGTTTATGAAGAAGAATATGGCTCAAGCCTGGAAGATGAC
GTGGTGGGGGACACTTCAGGGTACTACCAGCGGATGTTGGTGGTTCTCCTTCAGGCTAAC
AGAGACCCTGATGCTGGAATTGATGAAGCTCAAGTTGAACAAGATGCTCAGGCTTTATTT
CAGGCTGGAGAACTTAAATGGGGGACAGATGAAGAAAAGTTTATCACCATCTTTGGAACA
CGAAGTGTGTCTCATTTGAGAAAGGTGTTTGACAAGTACATGACTATATCAGGATTTCAA
ATTGAGGAAACCATTGACCGCGAGACTTCTGGCAATTTAGAGCAACTACTCCTTGCTGTT
GTGAAATCTATTCGAAGTATACCTGCCTACCTTGCAGAGACCCTCTATTATGCTATGAAG
GGAGCTGGGACAGATGATCATACCCTCATCAGAGTCATGGTTTCCAGGAGTGAGATTGAT
CTGTTTAACATCAGGAAGGAGTTTAGGAAGAATTTTGCCACCTCTCTTTATTCCATGATT
AAGGGAGATACATCTGGGGACTATAAGAAAGCTCTTCTGCTGCTCTGTGGAGAAGATGAC
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 320 |
| Molecular Weight
| 35936.4 |
| Theoretical pI
| 4.66 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Annexin A5
MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTL
FGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPE
ELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALF
QAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAV
VKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMI
KGDTSGDYKKALLLLCGEDD
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P08758 |
| UniProtKB/Swiss-Prot Entry Name
| ANXA5_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M18366 |
| GeneCard ID
| ANXA5 |
| GenAtlas ID
| ANXA5 |
| HGNC ID
| HGNC:543 |
| References |
|---|
| General References
| Not Available |