Showing Protein Calcitonin gene-related peptide 1 (CDBP01785)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP01785
Secondary Accession Numbers Not Available
Name Calcitonin gene-related peptide 1
Description Not Available
Synonyms
  1. Alpha-type CGRP
  2. CGRP-I
  3. Calcitonin gene-related peptide I
Gene Name CALCA
Protein Type Receptor
Biological Properties
General Function Involved in hormone activity
Specific Function CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP
GO Classification
Component
extracellular region
Function
hormone activity
binding
protein binding
receptor binding
Process
multicellular organismal process
system process
circulatory system process
vascular process in circulatory system
regulation of blood vessel size
vasodilation
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs CALCA
Gene Sequence 
>387 bp
ATGGGCTTCCAAAAGTTCTCCCCCTTCCTGGCTCTCAGCATCTTGGTCCTGTTGCAGGCA
GGCAGCCTCCATGCAGCACCATTCAGGTCTGCCCTGGAGAGCAGCCCAGCAGACCCGGCC
ACGCTCAGTGAGGACGAAGCGCGCCTCCTGCTGGCTGCACTGGTGCAGGACTATGTGCAG
ATGAAGGCCAGTGAGCTGGAGCAGGAGCAAGAGAGAGAGGGCTCCAGAATCATTGCCCAG
AAGAGAGCCTGTGACACTGCCACCTGTGTGACTCATCGGCTGGCAGGCTTGCTGAGCAGA
TCAGGGGGTGTGGTGAAGAACAACTTTGTGCCCACCAATGTGGGTTCCAAAGCCTTTGGC
AGGCGCCGCAGGGACCTTCAAGCCTGA
Protein Properties
Number of Residues 128
Molecular Weight 13897.8
Theoretical pI 9.97
Pfam Domain Function
Signals
  • ["1-25"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Calcitonin gene-related peptide 1
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQNYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
GenBank ID Protein 76880478
UniProtKB/Swiss-Prot ID P06881
UniProtKB/Swiss-Prot Entry Name CALCA_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001033953.2
GeneCard ID CALCA
GenAtlas ID CALCA
HGNC ID HGNC:1437
References
General References Not Available