Identification |
HMDB Protein ID
| CDBP01760 |
Secondary Accession Numbers
| Not Available |
Name
| Carbonic anhydrase 1 |
Description
| Not Available |
Synonyms
|
- CA-I
- CAB
- Carbonate dehydratase I
- Carbonic anhydrase B
- Carbonic anhydrase I
|
Gene Name
| CA1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in carbonate dehydratase activity |
Specific Function
| Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
|
GO Classification
|
Biological Process |
small molecule metabolic process |
bicarbonate transport |
one-carbon metabolic process |
Cellular Component |
Golgi apparatus |
cytosol |
Component |
cell part |
intracellular part |
cytoplasm |
Function |
ion binding |
cation binding |
metal ion binding |
binding |
catalytic activity |
carbonate dehydratase activity |
transition metal ion binding |
zinc ion binding |
lyase activity |
carbon-oxygen lyase activity |
hydro-lyase activity |
Molecular Function |
zinc ion binding |
carbonate dehydratase activity |
metal ion binding |
Process |
metabolic process |
cellular metabolic process |
one-carbon metabolic process |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Gastric Acid Production | | Not Available | Esomeprazole Action Pathway | | Not Available | Omeprazole Action Pathway | | Not Available | Lansoprazole Action Pathway | | Not Available | Pantoprazole Action Pathway | | Not Available |
|
Gene Properties |
Chromosome Location
| 8 |
Locus
| 8q21.2 |
SNPs
| CA1 |
Gene Sequence
|
>786 bp
ATGGCAAGTCCAGACTGGGGATATGATGACAAAAATGGTCCTGAACAATGGAGCAAGCTG
TATCCCATTGCCAATGGAAATAACCAATCCCCTGTTGATATTAAAACCAGTGAAACCAAA
CATGACACCTCTCTGAAACCTATTAGTGTCTCCTACAACCCAGCCACAGCCAAAGAAATT
ATCAATGTGGGGCATTCTTTCCATGTAAATTTTGAGGACAACGATAACCGATCAGTGCTG
AAAGGTGGTCCTTTCTCTGACAGCTACAGGCTCTTTCAGTTTCATTTTCACTGGGGCAGT
ACAAATGAGCATGGTTCAGAACATACAGTGGATGGAGTCAAATATTCTGCCGAGCTTCAC
GTAGCTCACTGGAATTCTGCAAAGTACTCCAGCCTTGCTGAAGCTGCCTCAAAGGCTGAT
GGTTTGGCAGTTATTGGTGTTTTGATGAAGGTTGGTGAGGCCAACCCAAAGCTGCAGAAA
GTACTTGATGCCCTCCAAGCAATTAAAACCAAGGGCAAACGAGCCCCATTCACAAATTTT
GACCCCTCTACTCTCCTTCCTTCATCCCTGGATTTCTGGACCTACCCTGGCTCTCTGACT
CATCCTCCTCTTTATGAGAGTGTAACTTGGATCATCTGTAAGGAGAGCATCAGTGTCAGC
TCAGAGCAGCTGGCACAATTCCGCAGCCTTCTATCAAATGTTGAAGGTGATAACGCTGTC
CCCATGCAGCACAACAACCGCCCAACCCAACCTCTGAAGGGCAGAACAGTGAGAGCTTCA
TTTTGA
|
Protein Properties |
Number of Residues
| 261 |
Molecular Weight
| 28870.0 |
Theoretical pI
| 7.117 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Carbonic anhydrase 1
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
|
External Links |
GenBank ID Protein
| 29600 |
UniProtKB/Swiss-Prot ID
| P00915 |
UniProtKB/Swiss-Prot Entry Name
| CAH1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| X05014 |
GeneCard ID
| CA1 |
GenAtlas ID
| CA1 |
HGNC ID
| HGNC:1368 |
References |
General References
| Not Available |