Identification |
HMDB Protein ID
| CDBP01740 |
Secondary Accession Numbers
| Not Available |
Name
| Guanine nucleotide-binding protein G(q) subunit alpha |
Description
| Not Available |
Synonyms
|
- Guanine nucleotide-binding protein alpha-q
|
Gene Name
| GNAQ |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in signal transducer activity |
Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems |
GO Classification
|
Function |
gtp binding |
molecular transducer activity |
signal transducer activity |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
Process |
g-protein coupled receptor protein signaling pathway |
metabolic process |
macromolecule metabolic process |
protein amino acid adp-ribosylation |
biological regulation |
regulation of biological process |
post-translational protein modification |
regulation of cellular process |
signal transduction |
macromolecule modification |
protein modification process |
signaling |
signaling pathway |
cell surface receptor linked signaling pathway |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Activation of PKC through G protein coupled receptor | | Not Available | Chlorphenamine H1-Antihistamine Action | | Not Available | Pheniramine H1-Antihistamine Action | | Not Available | Dexchlorpheniramine H1-Antihistamine Action | | Not Available | Brompheniramine H1-Antihistamine Action | | Not Available |
|
Gene Properties |
Chromosome Location
| Chromosome:9 |
Locus
| 9q21 |
SNPs
| GNAQ |
Gene Sequence
|
>1080 bp
ATGACTCTGGAGTCCATCATGGCGTGCTGCCTGAGCGAGGAGGCCAAGGAAGCCCGGCGG
ATCAACGACGAGATCGAGCGGCACGTCCGCAGGGACAAGCGGGACGCCCGCCGGGAGCTC
AAGCTGCTGCTGCTCGGGACAGGAGAGAGTGGCAAGAGTACGTTTATCAAGCAGATGAGA
ATCATCCATGGGTCAGGATACTCTGATGAAGATAAAAGGGGCTTCACCAAGCTGGTGTAT
CAGAACATCTTCACGGCCATGCAGGCCATGATCAGAGCCATGGACACACTCAAGATCCCA
TACAAGTATGAGCACAATAAGGCTCATGCACAATTAGTTCGAGAAGTTGATGTGGAGAAG
GTGTCTGCTTTTGAGAATCCATATGTAGATGCAATAAAGAGTTTATGGAATGATCCTGGA
ATCCAGGAATGCTATGATAGACGACGAGAATATCAATTATCTGACTCTACCAAATACTAT
CTTAATGACTTGGACCGCGTAGCTGACCCTGCCTACCTGCCTACGCAACAAGATGTGCTT
AGAGTTCGAGTCCCCACCACAGGGATCATCGAATACCCCTTTGACTTACAAAGTGTCATT
TTCAGAATGGTCGATGTAGGGGGCCAAAGGTCAGAGAGAAGAAAATGGATACACTGCTTT
GAAAATGTCACCTCTATCATGTTTCTAGTAGCGCTTAGTGAATATGATCAAGTTCTCGTG
GAGTCAGACAATGAGAACCGAATGGAGGAAAGCAAGGCTCTCTTTAGAACAATTATCACA
TACCCCTGGTTCCAGAACTCCTCGGTTATTCTGTTCTTAAACAAGAAAGATCTTCTAGAG
GAGAAAATCATGTATTCCCATCTAGTCGACTACTTCCCAGAATATGATGGACCCCAGAGA
GATGCCCAGGCAGCCCGAGAATTCATTCTGAAGATGTTCGTGGACCTGAACCCAGACAGT
GACAAAATTATCTACTCCCACTTCACGTGCGCCACAGACACCGAGAATATCCGCTTTGTC
TTTGCTGCCGTCAAGGACACCATCCTCCAGTTGAACCTGAAGGAGTACAATCTGGTCTAA
|
Protein Properties |
Number of Residues
| 359 |
Molecular Weight
| 42141.7 |
Theoretical pI
| 5.37 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Guanine nucleotide-binding protein G(q) subunit alpha
MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR
IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK
VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL
RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV
ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR
DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
|
External Links |
GenBank ID Protein
| 1181671 |
UniProtKB/Swiss-Prot ID
| P50148 |
UniProtKB/Swiss-Prot Entry Name
| GNAQ_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| U40038 |
GeneCard ID
| GNAQ |
GenAtlas ID
| GNAQ |
HGNC ID
| HGNC:4390 |
References |
General References
| Not Available |