Identification |
HMDB Protein ID
| CDBP01736 |
Secondary Accession Numbers
| Not Available |
Name
| Molybdenum cofactor biosynthesis protein 1 |
Description
| Not Available |
Synonyms
|
- MOCS1A
- Cell migration-inducing gene 11 protein
- Molybdenum cofactor biosynthesis protein A
- Molybdenum cofactor biosynthesis protein C
- Molybdenum cofactor synthesis-step 1 protein A-B
|
Gene Name
| MOCS1 |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Coenzyme transport and metabolism |
Specific Function
| Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z).
|
GO Classification
|
Biological Process |
Mo-molybdopterin cofactor biosynthetic process |
water-soluble vitamin metabolic process |
Cellular Component |
cytosol |
molybdopterin synthase complex |
nucleus |
Component |
molybdopterin synthase complex |
macromolecular complex |
protein complex |
unlocalized protein complex |
Function |
iron ion binding |
4 iron, 4 sulfur cluster binding |
ion binding |
cation binding |
metal ion binding |
binding |
catalytic activity |
transition metal ion binding |
metal cluster binding |
iron-sulfur cluster binding |
Molecular Function |
metal ion binding |
4 iron, 4 sulfur cluster binding |
GTP binding |
catalytic activity |
Process |
mo-molybdopterin cofactor biosynthetic process |
coenzyme biosynthesis |
mo-molybdopterin cofactor biosynthesis |
metabolic process |
cellular metabolism |
cofactor metabolism |
coenzyme metabolism |
coenzyme biosynthetic process |
cellular metabolic process |
physiological process |
metabolism |
cofactor metabolic process |
coenzyme metabolic process |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | molybdopterin biosynthesis | Not Available | Not Available | Folate biosynthesis | Not Available | | Sulfur relay system | Not Available | |
|
Gene Properties |
Chromosome Location
| 6 |
Locus
| 6p21.3 |
SNPs
| MOCS1 |
Gene Sequence
|
>1158 bp
ATGGCGGCGCGGCCACTGTCCCGGATGCTGCGGCGGCTTCTGAGGTCCAGCGCCCGGAGC
TGCAGCTCAGGGGCTCCGGTGACCCAGCCCTGCCCCGGGGAGTCCGCGCGAGCTGCCTCG
GAGGAGGTGTCCAGGCGGAGGCAGTTCCTGCGGGAGCATGCGGCCCCCTTCTCCGCCTTC
CTCACAGACAGCTTCGGCCGGCAGCACAGCTACCTGCGGATCTCCCTCACAGAGAAGTGC
AACCTCAGATGTCAGTACTGCATGCCCGAGGAGGGGGTCCCGCTGACCCCCAAAGCCAAC
CTGCTGACCACAGAGGAGATCCTGACCCTCGCCCGGCTCTTTGTGAAGGAAGGCATCGAC
AAGATCCGGCTCACAGGTGGAGAGCCGCTTATCCGGCCGGACGTGGTGGACATTGTGGCC
CAGCTCCAGCGGCTGGAAGGGCTGAGAACCATAGGTGTTACCACCAATGGCATCAACCTG
GCCCGGCTACTGCCCCAGCTTCAGAAGGCTGGTCTCAGTGCCATCAACATCAGCCTGGAC
ACCCTGGTGCCTGCCAAGTTTGAGTTCATTGTCCGCAGGAAAGGCTTCCACAAGGTCATG
GAGGGCATCCACAAGGCCATCGAGCTGGGCTACAACCCTGTGAAGGTGAACTGTGTGGTG
ATGCGAGGCCTTAACGAGGATGAACTCCTGGACTTTGCGGCCTTGACTGAGGGCCACCCC
CTGGATGTGCGCTTCATAGAGTATATGCCCTTTGATGGCAACAAGTGGAACTTCAAGAAG
ATGGTCAGCTATAAGGAGATGCTAGACACTGTCCGGCAGCAGTGGCCAGAGCTGGAGAAG
GTGCCAGAGGAGGAATCCAGCACAGCCAAGGCCTTTAAAATCCCTGGCTTCCAAGGCCAG
ATCAGCTTCATCACATCCATGTCTGAGCATTTCTGTGGGACCTGCAACCGCCTGCGAATC
ACAGCTGATGGGAACCTCAAGGTCTGCCTCTTTGGAAACTCTGAGGTATCCCTGCGGGAT
CACCTGCGAGCTGGGGCCTCTGAGCAGGAGCTGCTGAGAATCATTGGGGCTGCTGTGGGC
AGGAAGAAGCGGCAGCATGCAGGCATGTTCAGTATTTCCCAGATGAAGAACCGGCCCATG
ATCCTCATCGGTGGGTGA
|
Protein Properties |
Number of Residues
| 385 |
Molecular Weight
| 43087.69 |
Theoretical pI
| 9.291 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Molybdenum cofactor biosynthesis protein 1 A
MAARPLSRMLRRLLRSSARSCSSGAPVTQPCPGESARAASEEVSRRRQFLREHAAPFSAF
LTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGID
KIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLD
TLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLP
LDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKAFKIPGFQGQ
ISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLRAGASEQELLRIIGAAVG
RKKRQHAGMFSISQMKNRPMILIGG
|
External Links |
GenBank ID Protein
| 2645879 |
UniProtKB/Swiss-Prot ID
| Q9NZB8 |
UniProtKB/Swiss-Prot Entry Name
| MOS1A_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF034374 |
GeneCard ID
| MOCS1 |
GenAtlas ID
| MOCS1 |
HGNC ID
| HGNC:7190 |
References |
General References
| Not Available |