| Identification |
|---|
| HMDB Protein ID
| CDBP01699 |
| Secondary Accession Numbers
| Not Available |
| Name
| Fibrinogen gamma chain |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| FGG |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in receptor binding |
| Specific Function
| Fibrinogen has a double function:yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation |
| GO Classification
|
| Component |
| extracellular region part |
| macromolecular complex |
| protein complex |
| extracellular space |
| fibrinogen complex |
| Function |
| binding |
| protein binding |
| receptor binding |
| protein binding, bridging |
| Process |
| cellular process |
| cellular component organization or biogenesis |
| biological regulation |
| cellular component organization |
| regulation of biological process |
| cellular component assembly |
| macromolecular complex assembly |
| cellular protein complex assembly |
| regulation of cellular process |
| signal transduction |
| protein complex assembly |
| protein polymerization |
| cell activation |
| platelet activation |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Acenocoumarol Action Pathway |    | Not Available | | Coagulation |    | Not Available | | Enoxaparin Action Pathway |    | Not Available | | Fondaparinux Action Pathway |    | Not Available | | Heparin Action Pathway |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q28 |
| SNPs
| FGG |
| Gene Sequence
|
>1362 bp
ATGAGTTGGTCCTTGCACCCCCGGAATTTAATTCTCTACTTCTATGCTCTTTTATTTCTC
TCTTCAACATGTGTAGCATATGTTGCTACCAGAGACAACTGCTGCATCTTAGATGAAAGA
TTCGGTAGTTATTGTCCAACTACCTGTGGCATTGCAGATTTCCTGTCTACTTATCAAACC
AAAGTAGACAAGGATCTACAGTCTTTGGAAGACATCTTACATCAAGTTGAAAACAAAACA
TCAGAAGTCAAACAGCTGATAAAAGCAATCCAACTCACTTATAATCCTGATGAATCATCA
AAACCAAATATGATAGACGCTGCTACTTTGAAGTCCAGGAAAATGTTAGAAGAAATTATG
AAATATGAAGCATCGATTTTAACACATGACTCAAGTATTCGATATTTGCAGGAAATATAT
AATTCAAATAATCAAAAGATTGTTAACCTGAAAGAGAAGGTAGCCCAGCTTGAAGCACAG
TGCCAGGAACCTTGCAAAGACACGGTGCAAATCCATGATATCACTGGGAAAGATTGTCAA
GACATTGCCAATAAGGGAGCTAAACAGAGCGGGCTTTACTTTATTAAACCTCTGAAAGCT
AACCAGCAATTCTTAGTCTACTGTGAAATCGATGGGTCTGGAAATGGATGGACTGTGTTT
CAGAAGAGACTTGATGGCAGTGTAGATTTCAAGAAAAACTGGATTCAATATAAAGAAGGA
TTTGGACATCTGTCTCCTACTGGCACAACAGAATTTTGGCTGGGAAATGAGAAGATTCAT
TTGATAAGCACACAGTCTGCCATCCCATATGCATTAAGAGTGGAACTGGAAGACTGGAAT
GGCAGAACCAGTACTGCAGACTATGCCATGTTCAAGGTGGGACCTGAAGCTGACAAGTAC
CGCCTAACATATGCCTACTTCGCTGGTGGGGATGCTGGAGATGCCTTTGATGGCTTTGAT
TTTGGCGATGATCCTAGTGACAAGTTTTTCACATCCCATAATGGCATGCAGTTCAGTACC
TGGGACAATGACAATGATAAGTTTGAAGGCAACTGTGCTGAACAGGATGGATCTGGTTGG
TGGATGAACAAGTGTCACGCTGGCCATCTCAATGGAGTTTATTACCAAGGTGGCACTTAC
TCAAAAGCATCTACTCCTAATGGTTATGATAATGGCATTATTTGGGCCACTTGGAAAACC
CGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATT
GGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGTCAGACCAGAGCACCCTGCG
GAAACAGAATATGACTCACTTTACCCTGAGGATGATTTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 453 |
| Molecular Weight
| 51511.3 |
| Theoretical pI
| 5.32 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Fibrinogen gamma chain
MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
|
| External Links |
|---|
| GenBank ID Protein
| 70906439 |
| UniProtKB/Swiss-Prot ID
| P02679 |
| UniProtKB/Swiss-Prot Entry Name
| FIBG_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_021870.2 |
| GeneCard ID
| FGG |
| GenAtlas ID
| FGG |
| HGNC ID
| HGNC:3694 |
| References |
|---|
| General References
| Not Available |