| Identification |
|---|
| HMDB Protein ID
| CDBP01680 |
| Secondary Accession Numbers
| Not Available |
| Name
| Zinc finger protein 24 |
| Description
| Not Available |
| Synonyms
|
- RSG-A
- Retinoic acid suppression protein A
- Zinc finger and SCAN domain-containing protein 3
- Zinc finger protein 191
- Zinc finger protein KOX17
|
| Gene Name
| ZNF24 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in viral reproduction |
| Specific Function
| Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically bind to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro |
| GO Classification
|
| Component |
| cell part |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| nucleus |
| intracellular |
| Function |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
| nucleic acid binding |
| sequence-specific dna binding transcription factor activity |
| ion binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of macromolecule metabolic process |
| regulation of gene expression |
| regulation of transcription |
| regulation of transcription, dna-dependent |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q12 |
| SNPs
| ZNF24 |
| Gene Sequence
|
>1107 bp
ATGTCTGCACAGTCAGTGGAAGAAGATTCAATACTTATCATCCCAACTCCAGATGAAGAG
GAAAAAATTCTGAGAGTGAAGTTGGAGGAGGATCCTGATGGCGAAGAGGGATCAAGTATC
CCCTGGAACCATCTCCCAGACCCAGAGATTTTCCGACAGCGATTCAGGCAGTTTGGATAC
CAGGATTCACCTGGGCCCCGTGAGGCTGTGAGCCAGCTCCGAGAACTTTGCCGTCTGTGG
CTCAGGCCAGAGACGCACACAAAAGAACAAATCTTGGAGCTGGTAGTGCTGGAGCAGTTT
GTTGCCATCCTACCCAAAGAGCTACAGACTTGGGTTCGAGATCATCATCCAGAGAATGGA
GAGGAGGCAGTGACAGTGCTGGAGGATTTGGAGAGTGAACTTGATGACCCTGGACAACCG
GTTTCTCTCCGTCGACGAAAACGGGAAGTACTAGTAGAAGACATGGTATCTCAAGAAGAA
GCTCAGGGATTACCAAGTTCTGAGCTTGATGCTGTGGAGAACCAGCTCAAGTGGGCATCC
TGGGAGCTCCATTCCCTAAGGCACTGTGATGATGATGGTAGGACTGAAAATGGAGCACTA
GCTCCAAAGCAGGAGCTTCCTTCAGCATTAGAATCCCATGAAGTTCCTGGCACTCTCAAT
ATGGGTGTTCCTCAAATTTTTAAATATGGAGAAACCTGTTTCCCCAAGGGCAGGTTTGAA
AGAAAGAGAAATCCCTCTCGAAAGAAACAACATATATGTGATGAATGTGGAAAACACTTC
AGTCAGGGCTCAGCCCTTATTCTTCATCAAAGAATTCACAGTGGGGAGAAACCTTATGGA
TGTGTTGAGTGTGGGAAAGCATTCAGCCGAAGTTCCATTCTTGTGCAACACCAGAGAGTC
CACACTGGAGAAAAACCTTACAAATGTCTTGAATGTGGGAAAGCCTTTAGCCAGAATTCG
GGGCTTATTAATCATCAGAGAATCCATACTGGGGAGAAACCTTATGAATGCGTTCAGTGT
GGGAAATCGTATAGTCAAAGCTCAAATCTTTTTAGACATCAGAGAAGACACAATGCAGAA
AAACTTCTGAATGTTGTGAAAGTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 368 |
| Molecular Weight
| 42155.1 |
| Theoretical pI
| 6.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Zinc finger protein 24
MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY
QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG
EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS
WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFE
RKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRV
HTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAE
KLLNVVKV
|
| External Links |
|---|
| GenBank ID Protein
| 190610012 |
| UniProtKB/Swiss-Prot ID
| P17028 |
| UniProtKB/Swiss-Prot Entry Name
| ZNF24_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_006965.2 |
| GeneCard ID
| ZNF24 |
| GenAtlas ID
| ZNF24 |
| HGNC ID
| HGNC:13032 |
| References |
|---|
| General References
| Not Available |