Identification |
HMDB Protein ID
| CDBP01653 |
Secondary Accession Numbers
| Not Available |
Name
| Cyclic AMP-responsive element-binding protein 5 |
Description
| Not Available |
Synonyms
|
- CRE-BPa
- CREB-5
- cAMP-responsive element-binding protein 5
|
Gene Name
| CREB5 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in sequence-specific DNA binding transcription factor activity |
Specific Function
| Binds to the cAMP response element and activates transcription |
GO Classification
|
Component |
cell part |
intracellular |
Function |
ion binding |
cation binding |
metal ion binding |
binding |
transition metal ion binding |
zinc ion binding |
protein binding |
nucleic acid binding |
dna binding |
protein dimerization activity |
sequence-specific dna binding |
sequence-specific dna binding transcription factor activity |
Process |
biological regulation |
regulation of biological process |
regulation of metabolic process |
regulation of macromolecule metabolic process |
regulation of gene expression |
regulation of transcription |
regulation of transcription, dna-dependent |
|
Cellular Location
|
- Nucleus (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:7 |
Locus
| 7p15.1 |
SNPs
| CREB5 |
Gene Sequence
|
>1527 bp
ATGATTTATGAGGAATCCAAGATGAATTTGGAGCAGGAGAGGCCGTTTGTCTGCAGTGCC
CCAGGCTGCTCCCAGCGCTTCCCAACAGAGGACCATCTGATGATTCATAGGCACAAACAT
GAAATGACTTTGAAGTTTCCTTCAATAAAAACAGACAATATGTTATCAGATCAAACTCCG
ACCCCAACGAGATTCCTGAAGAACTGCGAGGAGGTGGGCCTCTTCAGCGAGCTGGACTGC
TCCCTGGAGCACGAGTTCAGGAAGGCTCAGGAAGAGGAGAGCAGCAAGCGGAATATCTCG
ATGCATAATGCAGTTGGTGGGGCCATGACGGGGCCCGGAACTCACCAGCTTAGCAGCGCT
CGGCTGCCCAACCATGACACCAACGTTGTGATTCAGCAAGCCATGCCGTCGCCTCAGTCC
AGCTCTGTCATCACTCAGGCACCTTCCACCAACCGCCAGATCGGGCCTGTCCCAGGCTCT
CTATCTTCTCTGCTACATCTCCACAACAGACAGAGACAGCCCATGCCAGCCTCCATGCCT
GGGACCCTGCCCAACCCTACAATGCCAGGATCTTCCGCCGTCTTGATGCCAATGGAGCGA
CAAATGTCAGTGAACTCCAGCATCATGGGGATGCAAGGTCCAAATCTCAGCAACCCCTGT
GCTTCTCCCCAGGTCCAGCCAATGCATTCAGAAGCCAAAATGAGGTTGAAGGCTGCATTG
ACTCACCACCCTGCTGCCATGTCAAATGGGAACATGAACACCATGGGACACATGATGGAG
ATGATGGGCTCCCGGCAGGACCAGACGCCACACCATCACATGCACTCGCACCCGCATCAG
CACCAGACACTGCCACCCCATCACCCTTACCCACACCAGCACCAGCACCCAGCACACCAT
CCTCACCCTCAACCCCATCACCAGCAGAACCATCCACATCACCACTCCCATTCCCACCTT
CATGCACACCCAGCACATCACCAGACCTCGCCACATCCGCCCCTGCACACCGGCAACCAA
GCACAGGTTTCACCAGCAACACAACAGATGCAGCCAACCCAGACAATACAGCCACCCCAG
CCCACAGGGGGGCGCCGGCGAAGGGTGGTAGACGAGGATCCGGACGAGAGGCGGCGGAAA
TTTCTGGAACGGAACCGGGCAGCTGCCACCCGCTGCAGACAGAAGAGGAAGGTCTGGGTG
ATGTCATTGGAAAAGAAAGCAGAAGAACTCACCCAGACAAACATGCAGCTTCAGAATGAA
GTGTCTATGTTGAAAAATGAGGTGGCCCAGCTGAAACAGTTGTTGTTAACACATAAAGAC
TGCCCAATAACAGCCATGCAGAAAGAATCACAAGGATATCTAAGTCCAGAGAGTAGCCCT
CCTGCTAGTCCTGTCCCAGCTTGCTCCCAGCAACAAGTCATCCAGCATAATACCATCACT
ACTTCCTCATCGGTCAGCGAGGTGGTAGGAAGCTCCACCCTCAGCCAGCTCACCACTCAC
AGAACAGACCTGAATCCGATTCTTTAA
|
Protein Properties |
Number of Residues
| 508 |
Molecular Weight
| 56858.0 |
Theoretical pI
| 8.63 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Cyclic AMP-responsive element-binding protein 5
MIYEESKMNLEQERPSVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTP
TPTRFLKNCEEVGLFSELDCSLEHEFRKAQEEESSKRNISMHNAVGGAMTGPGTHQLSSA
RLPNHDTNVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMP
GTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAAL
THHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHH
PHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQ
PTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNE
VSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTIT
TSSSVSEVVGSSTLSQLTTHRTDLNPIL
|
External Links |
GenBank ID Protein
| 59938770 |
UniProtKB/Swiss-Prot ID
| Q02930 |
UniProtKB/Swiss-Prot Entry Name
| CREB5_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_182898.2 |
GeneCard ID
| CREB5 |
GenAtlas ID
| CREB5 |
HGNC ID
| HGNC:16844 |
References |
General References
| Not Available |