| Identification |
|---|
| HMDB Protein ID
| CDBP01564 |
| Secondary Accession Numbers
| Not Available |
| Name
| Beta-2-glycoprotein 1 |
| Description
| Not Available |
| Synonyms
|
- APC inhibitor
- Activated protein C-binding protein
- Anticardiolipin cofactor
- Apo-H
- Apolipoprotein H
- B2GPI
- Beta(2)GPI
- Beta-2-glycoprotein I
|
| Gene Name
| APOH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in eukaryotic cell surface binding |
| Specific Function
| Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q23-qter |
| SNPs
| APOH |
| Gene Sequence
|
>1038 bp
ATGATTTCTCCAGTGCTCATCTTGTTCTCGAGTTTTCTCTGCCATGTTGCTATTGCAGGA
CGGACCTGTCCCAAGCCAGATGATTTACCATTTTCCACAGTGGTCCCGTTAAAAACATTC
TATGAGCCAGGAGAAGAGATTACGTATTCCTGCAAGCCGGGCTATGTGTCCCGAGGAGGG
ATGAGAAAGTTTATCTGCCCTCTCACAGGACTGTGGCCCATCAACACTCTGAAATGTACA
CCCAGAGTATGTCCTTTTGCTGGAATCTTAGAAAATGGAGCCGTACGCTATACGACTTTT
GAATATCCCAACACGATCAGTTTTTCTTGTAACACTGGGTTTTATCTGAATGGCGCTGAT
TCTGCCAAGTGCACTGAGGAAGGAAAATGGAGCCCGGAGCTTCCTGTCTGTGCTCCCATC
ATCTGCCCTCCACCATCCATACCTACGTTTGCAACACTTCGTGTTTATAAGCCATCAGCT
GGAAACAATTCCCTCTATCGGGACACAGCAGTTTTTGAATGTTTGCCACAACATGCGATG
TTTGGAAATGATACAATTACCTGCACGACACATGGAAATTGGACTAAATTACCAGAATGC
AGGGAAGTAAAATGCCCATTCCCATCAAGACCAGACAATGGATTTGTGAACTATCCTGCA
AAACCAACACTTTATTACAAGGATAAAGCCACATTTGGCTGCCATGATGGATATTCTCTG
GATGGCCCGGAAGAAATAGAATGTACCAAACTGGGAAACTGGTCTGCCATGCCAAGTTGT
AAAGCATCTTGTAAATTACCTGTGAAAAAAGCCACTGTGGTGTACCAAGGAGAGAGAGTA
AAGATTCAGGAAAAATTTAAGAATGGAATGCTACATGGTGATAAAGTTTCTTTCTTCTGC
AAAAATAAGGAAAAGAAGTGTAGCTATACAGAGGATGCTCAGTGTATAGATGGCACTATC
GAAGTCCCCAAATGCTTCAAGGAACACAGTTCTCTGGCTTTTTGGAAAACTGATGCATCC
GATGTAAAGCCATGCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 345 |
| Molecular Weight
| 38297.8 |
| Theoretical pI
| 8.03 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Beta-2-glycoprotein 1
MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG
MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD
SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM
FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL
DGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC
KNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
|
| External Links |
|---|
| GenBank ID Protein
| 28810 |
| UniProtKB/Swiss-Prot ID
| P02749 |
| UniProtKB/Swiss-Prot Entry Name
| APOH_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| X58100 |
| GeneCard ID
| APOH |
| GenAtlas ID
| APOH |
| HGNC ID
| HGNC:616 |
| References |
|---|
| General References
| Not Available |