Cannabis Compound Database: Showing Protein Beta-1,3-galactosyltransferase 2 (CDBP01549)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP01549

Secondary Accession Numbers

Not Available

Name

Beta-1,3-galactosyltransferase 2

Description

Not Available

Synonyms

Beta-1,3-GalTase 2
Beta3Gal-T2
Beta3GalT2
UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2

Gene Name

B3GALT2

Protein Type

Enzyme

Biological Properties

General Function

Involved in galactosyltransferase activity

Specific Function

Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues

GO Classification

Component
membrane
cell part
Function
galactosyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring hexosyl groups
transferase activity, transferring glycosyl groups
Process
protein amino acid glycosylation
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process

Cellular Location

Golgi apparatus membrane
Single-pass type II membrane protein (Probable)

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1q31

SNPs

B3GALT2

Gene Sequence

>1269 bp
ATGCTTCAGTGGAGGAGAAGACACTGCTGCTTTGCAAAGATGACCTGGAATGCCAAAAGG
TCTCTGTTCCGCACTCATCTTATTGGAGTACTTTCTCTAGTGTTTCTTTTTGCTATGTTT
TTGTTTTTCAATCATCATGACTGGCTGCCAGGCAGAGCTGGATTCAAAGAAAACCCTGTG
ACATACACTTTCCGAGGATTTCGGTCAACAAAAAGTGAGACAAACCACAGCTCCCTTCGG
AACATTTGGAAAGAAACAGTCCCTCAAACCCTGAGGCCTCAAACAGCAACTAACTCTAAT
AACACAGACCTGTCACCACAAGGAGTTACAGGCCTGGAGAATACACTTAGTGCCAATGGA
AGTATTTACAATGAAAAAGGTACTGGACATCCAAATTCTTACCATTTCAAATATATTATT
AATGAGCCTGAAAAATGCCAAGAGAAAAGTCCTTTTTTAATACTACTAATAGCTGCAGAG
CCTGGACAAATAGAAGCTAGAAGAGCTATTCGGCGAACTTGGGGCAATGAAAGTCTAGCA
CCTGGTATTCAAATCACAAGAATATTTTTGTTGGGCTTAAGTATTAAGCTAAATGGCTAC
CTTCAACGTGCAATACTGGAAGAAAGCAGACAATATCATGATATAATTCAACAGGAATAC
TTAGATACGTACTATAATTTGACCATTAAAACACTAATGGGCATGAACTGGGTTGCAACA
TACTGTCCACATATTCCATATGTTATGAAAACTGACAGTGACATGTTTGTCAACACTGAA
TATTTAATCAATAAGTTACTGAAGCCAGATCTGCCTCCCAGACATAACTATTTCACTGGT
TACCTAATGCGAGGATATGCACCCAATCGAAACAAAGATAGCAAGTGGTACATGCCACCA
GACCTCTACCCAAGTGAGCGTTATCCTGTCTTCTGTTCTGGAACTGGTTATGTTTTTTCT
GGAGATCTGGCAGAAAAGATTTTTAAAGTTTCTTTAGGTATCCGCCGTTTGCACTTGGAA
GATGTATATGTAGGGATCTGTCTTGCCAAGTTGAGAATTGATCCTGTACCCCCTCCCAAT
GAGTTTGTGTTCAATCACTGGCGAGTCTCTTATTCGAGCTGTAAATACAGCCACCTAATT
ACCTCTCATCAGTTCCAGCCTAGTGAACTGATAAAATACTGGAACCATTTACAACAAAAT
AAGCACAATGCCTGTGCCAACGCAGCAAAAGAAAAGGCAGGCAGGTATCGCCACCGTAAA
CTACATTAG

Protein Properties

Number of Residues

422

Molecular Weight

49213.1

Theoretical pI

9.81

Pfam Domain Function

Galactosyl_T (PF01762 )

Signals

["None"]

Transmembrane Regions

["25-45"]

Protein Sequence

>Beta-1,3-galactosyltransferase 2
MLQWRRRHCCFAKMTWNAKRSLFRTHLIGVLSLVFLFAMFLFFNHHDWLPGRAGFKENPV
TYTFRGFRSTKSETNHSSLRNIWKETVPQTLRPQTATNSNNTDLSPQGVTGLENTLSANG
SIYNEKGTGHPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNESLA
PGIQITRIFLLGLSIKLNGYLQRAILEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVAT
YCPHIPYVMKTDSDMFVNTEYLINKLLKPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMPP
DLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPVPPPN
EFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRK
LH

External Links

GenBank ID Protein

12620190

UniProtKB/Swiss-Prot ID

O43825

UniProtKB/Swiss-Prot Entry Name

B3GT2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF288390

GeneCard ID