Identification
HMDB Protein ID CDBP01528
Secondary Accession Numbers Not Available
Name Histidine triad nucleotide-binding protein 1
Description Not Available
Synonyms
  1. Adenosine 5'-monophosphoramidase
  2. PKCI-1
  3. Protein kinase C inhibitor 1
  4. Protein kinase C-interacting protein 1
Gene Name HINT1
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha- acetyl lysine methyl ester and AMP-NH2
GO Classification
Function
catalytic activity
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31.2
SNPs HINT1
Gene Sequence
>381 bp
ATGGCAGATGAGATTGCCAAGGCTCAGGTCGCTCGGCCTGGTGGCGACACGATCTTTGGG
AAGATCATCCGCGAGGAAATACCAGCCAAAATCATTTTTGAGGATGACCGGTGCCTTGCT
TTCCATGACATTTCCCCTCAAGCACCAACACATTTTCTGGTGATACCCAAGAAACATATA
TCCCAGATTTCTGTGGCAGAAGATGATGATGAAAGTCTTCTTGGACACTTAATGATTGTT
GGCAAGAAATGTGCTGCTGATCTGGGCCTGAATAAGGGTTATCGAATGGTGGTGAATGAA
GGTTCAGATGGTGGACAGTCTGTCTATCACGTTCATCTCCATGTTCTTGGAGGTCGGCAA
ATGCATTGGCCTCCTGGTTAA
Protein Properties
Number of Residues 126
Molecular Weight 13801.8
Theoretical pI 6.96
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Histidine triad nucleotide-binding protein 1
MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI
SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ
MHWPPG
GenBank ID Protein 10439439
UniProtKB/Swiss-Prot ID P49773
UniProtKB/Swiss-Prot Entry Name HINT1_HUMAN
PDB IDs
GenBank Gene ID AK026557
GeneCard ID HINT1
GenAtlas ID HINT1
HGNC ID HGNC:4912
References
General References Not Available