| Identification |
|---|
| HMDB Protein ID
| CDBP01508 |
| Secondary Accession Numbers
| Not Available |
| Name
| Hemoglobin subunit gamma-1 |
| Description
| Not Available |
| Synonyms
|
- Gamma-1-globin
- Hb F Agamma
- Hemoglobin gamma-1 chain
- Hemoglobin gamma-A chain
|
| Gene Name
| HBG1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in iron ion binding |
| Specific Function
| Gamma chains make up the fetal hemoglobin F, in combination with alpha chains |
| GO Classification
|
| Component |
| macromolecular complex |
| protein complex |
| hemoglobin complex |
| Function |
| metal ion binding |
| binding |
| transition metal ion binding |
| iron ion binding |
| heme binding |
| oxygen binding |
| ion binding |
| cation binding |
| Process |
| establishment of localization |
| transport |
| gas transport |
| oxygen transport |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p15.5 |
| SNPs
| HBG1 |
| Gene Sequence
|
>444 bp
ATGGGTCATTTCACAGAGGAGGACAAGGCTACTATCACAAGCCTGTGGGGCAAGGTGAAT
GTGGAAGATGCTGGAGGAGAAACCCTGGGAAGGCTCCTGGTTGTCTACCCATGGACCCAG
AGGTTCTTTGACAGCTTTGGCAACCTGTCCTCTGCCTCTGCCATCATGGGCAACCCCAAA
GTCAAGGCACATGGCAAGAAGGTGCTGACTTCCTTGGGAGATGCCATAAAGCACCTGGAT
GATCTCAAGGGCACCTTTGCCCAGCTGAGTGAACTGCACTGTGACAAGCTGCATGTGGAT
CCTGAGAACTTCAAGCTCCTGGGAAATGTGCTGGTGACCGTTTTGGCAATCCATTTCGGC
AAAGAATTCACCCCTGAGGTGCAGGCTTCCTGGCAGAAGATGGTGACTGCAGTGGCCAGT
GCCCTGTCCTCCAGATACCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 147 |
| Molecular Weight
| 16140.4 |
| Theoretical pI
| 7.23 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Hemoglobin subunit gamma-1
MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
KEFTPEVQASWQKMVTAVASALSSRYH
|
| External Links |
|---|
| GenBank ID Protein
| 11493500 |
| UniProtKB/Swiss-Prot ID
| P69891 |
| UniProtKB/Swiss-Prot Entry Name
| HBG1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF130098 |
| GeneCard ID
| HBG1 |
| GenAtlas ID
| HBG1 |
| HGNC ID
| HGNC:4831 |
| References |
|---|
| General References
| Not Available |