| Identification |
|---|
| HMDB Protein ID
| CDBP01484 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mitochondrial dicarboxylate carrier |
| Description
| Not Available |
| Synonyms
|
- Solute carrier family 25 member 10
|
| Gene Name
| SLC25A10 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in binding |
| Specific Function
| Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane |
| GO Classification
|
| Component |
| membrane |
| mitochondrion |
| cell part |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| Function |
| binding |
| Process |
| transmembrane transport |
| establishment of localization |
| transport |
| intracellular transport |
| mitochondrial transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | The Oncogenic Action of Succinate |    | Not Available | | The Oncogenic Action of Fumarate |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q25.3 |
| SNPs
| SLC25A10 |
| Gene Sequence
|
>864 bp
ATGGCAGCCGAGGCGCGCGTGTCGCGCTGGTACTTCGGGGGGCTGGCCTCCTGCGGGGCC
GCCTGCTGCACGCACCCGCTGGACCTGCTCAAGGTGCATCTGCAGACGCAGCAGGAGGTG
AAGCTGCGCATGACGGGCATGGCGCTGCGGGTGGTGCGTACCGACGGCATCCTGGCACTC
TACAGCGGCCTGAGCGCCTCGCTGTGCAGACAGATGACCTACTCCCTGACTCGGTTCGCC
ATCTACGAGACTGTGCGGGACCGCGTGGCCAAGGGCAGCCAGGGGCCTCTCCCCTTCCAC
GAGAAGGTGTTGCTGGGCTCCGTCAGCGGTTTAGCTGGAGGCTTCGTGGGGACGCCCGCA
GACTTGGTCAACGTCAGGATGCAGAACGACGTGAAGCTGCCCCAGGGTCAGCGGCGCAAC
TACGCCCATGCGCTGGATGGCCTGTACCGCGTAGCTCGTGAAGAGGGTCTCAGGAGACTG
TTCTCGGGTGCAACCATGGCATCCAGCCGAGGGGCCTTAGTCACTGTGGGCCAGCTGTCC
TGCTACGACCAGGCCAAGCAGCGGGTCCTTAGCACCGGGTACCTCTCTGACAACATCTTC
ACTCACTTTGTCGCCAGCTTTATTGCAGGTGGATGTGCCACGTTCCTGTGCCAGCCCCTG
GATGTGCTGAAGACTCGCCTGATGAACTCCAAGGGGGAGTATCAGGGCGTTTTCCACTGC
GCCGTGGAGACAGCGAAGCTCGGGCCTCTGGCCTTTTACAAGGGCCTCGTCCCAGCTGGC
ATCCGCCTCATCCCCCACACCGTGCTCACTTTTGTGTTTCTGGAACAGCTACGCAAAAAC
TTTGGCATCAAAGTGCCATCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 287 |
| Molecular Weight
| 31282.2 |
| Theoretical pI
| 9.91 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["10-30", "63-82", "103-123", "163-182", "203-223", "255-275"]
|
| Protein Sequence
|
>Mitochondrial dicarboxylate carrier
MAAEARVSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILAL
YSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPA
DLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLS
CYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHC
AVETAKLGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKNFGIKVPS
|
| External Links |
|---|
| GenBank ID Protein
| 6179584 |
| UniProtKB/Swiss-Prot ID
| Q9UBX3 |
| UniProtKB/Swiss-Prot Entry Name
| DIC_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ131613 |
| GeneCard ID
| SLC25A10 |
| GenAtlas ID
| SLC25A10 |
| HGNC ID
| HGNC:10980 |
| References |
|---|
| General References
| Not Available |