| Identification |
|---|
| HMDB Protein ID
| CDBP01475 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphoacetylglucosamine mutase |
| Description
| Not Available |
| Synonyms
|
- Acetylglucosamine phosphomutase
- N-acetylglucosamine-phosphate mutase
- PAGM
- PGM 3
- Phosphoglucomutase-3
|
| Gene Name
| PGM3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in intramolecular transferase activity, phosphotransferases |
| Specific Function
| Interconverts GlcNAc-6-P and GlcNAc-1-P.
|
| GO Classification
|
| Biological Process |
| hemopoiesis |
| UDP-N-acetylglucosamine biosynthetic process |
| dolichol-linked oligosaccharide biosynthetic process |
| post-translational protein modification |
| protein N-linked glycosylation via asparagine |
| glucosamine metabolic process |
| Cellular Component |
| cytosol |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| magnesium ion binding |
| isomerase activity |
| phosphoacetylglucosamine mutase activity |
| intramolecular transferase activity |
| intramolecular transferase activity, phosphotransferases |
| Molecular Function |
| magnesium ion binding |
| phosphoacetylglucosamine mutase activity |
| Process |
| primary metabolic process |
| carbohydrate metabolic process |
| metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | UDP-N-acetyl-alpha-D-glucosamine biosynthesis | Not Available | Not Available | | Amino sugar and nucleotide sugar metabolism | Not Available |  | | Amino Sugar Metabolism |    | | | Sialuria or French Type Sialuria |    | Not Available | | Salla Disease/Infantile Sialic Acid Storage Disease |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| 6q14.1-q15 |
| SNPs
| PGM3 |
| Gene Sequence
|
>1629 bp
ATGGATTTAGGTGCTATTACAAAATACTCAGCATTACACGCCAAGCCCAATGGACTGATC
CTTCAATACGGGACTGCTGGATTTCGAACGAAGGCAGAACATCTTGATCATGTCATGTTT
CGCATGGGATTATTAGCTGTCCTGAGGTCAAAACAGACAAAATCCACTATAGGAGTCATG
GTAACAGCGTCCCACAATCCTGAGGAAGACAATGGTGTAAAATTGGTTGATCCTTTGGGT
GAAATGTTGGCACCATCCTGGGAGGAACATGCCACCTGTTTAGCAAATGCTGAGGAACAA
GATATGCAGAGAGTGCTTATTGACATCAGCGAGAAAGAAGCTGTGAATCTGCAACAAGAT
GCCTTTGTAGTTATTGGTAGAGATACCAGGCCCAGCAGTGAGAAACTTTCACAATCTGTA
ATAGATGGTGTGACTGTTCTAGGAGGTCAATTCCATGATTATGGCTTGTTAACAACACCC
CAGCTGCACTACATGGTGTATTGTCGAAACACGGGTGGCCGATATGGAAAGGCAACTATA
GAAGGTTACTACCAGAAACTCTCTAAGGCTTTTGTGGAACTCACCAAACAGGCTTCTTGC
AGTGGAGATGAATACAGATCACTTAAGGTTGACTGTGCAAATGGCATAGGGGCCCTGAAG
CTAAGGGAAATGGAACACTACTTCTCACAGGGCCTGTCAGTTCAGCTGTTTAATGATGGG
TCCAAGGGCAAACTCAATCATTTATGTGGAGCTGACTTTGTGAAAAGTCATCAGAAACCT
CCACAGGGAATGGAAATTAAGTCCAATGAAAGATGCTGTTCTTTTGATGGAGATGCAGAC
AGAATTGTTTATTACTACCATGATGCAGATGGCCACTTTCATCTCATAGATGGAGACAAG
ATAGCAACGTTAATTAGCAGTTTCCTTAAAGAGCTCCTGGTGGAGATTGGAGAAAGTTTG
AATATTGGTGTTGTACAAACTGCATATGCAAATGGAAGTTCAACACGGTATCTTGAAGAA
GTTATGAAGGTACCTGTCTATTGCACTAAGACTGGTGTAAAACATTTGCACCACAAGGCT
CAAGAGTTTGACATTGGAGTTTATTTTGAAGCAAATGGGCATGGCACTGCACTGTTTAGT
ACAGCTGTTGAAATGAAGATAAAACAATCAGCAGAACAACTGGAAGATAAGAAAAGAAAA
GCTGCTAAGATGCTTGAAAACATTATTGACTTGTTTAACCAGGCAGCTGGTGATGCTATT
TCTGACATGCTGGTGATTGAAGCAATCTTGGCTCTGAAGGGCTTGACTGTACAACAGTGG
GATGCTCTCTATACAGATCTTCCAAACAGACAACTTAAAGTTCAGGTTGCAGACAGGAGA
GTTATTAGCACTACCGATGCTGAAAGACAAGCAGTTACACCCCCAGGATTACAGGAGGCA
ATCAATGACCTGGTGAAGAAGTACAAGCTTTCTCGAGCTTTTGTCCGGCCCTCTGGTACA
GAAGATGTCGTCCGAGTATATGCAGAAGCAGACTCACAAGAAAGTGCAGATCACCTTGCA
CATGAAGTGAGCTTGGCAGTATTTCAGCTGGCTGGAGGAATTGGAGAAAGGCCCCAACCA
GGTTTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 542 |
| Molecular Weight
| 62940.905 |
| Theoretical pI
| 5.999 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Phosphoacetylglucosamine mutase
MDLGAITKYSALHAKPNGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVM
VTASHNPEEDNGVKLVDPLGEMLAPSWEEHATCLANAEEQDMQRVLIDISEKEAVNLQQD
AFVVIGRDTRPSSEKLSQSVIDGVTVLGGQFHDYGLLTTPQLHYMVYCRNTGGRYGKATI
EGYYQKLSKAFVELTKQASCSGDEYRSLKVDCANGIGALKLREMEHYFSQGLSVQLFNDG
SKGKLNHLCGADFVKSHQKPPQGMEIKSNERCCSFDGDADRIVYYYHDADGHFHLIDGDK
IATLISSFLKELLVEIGESLNIGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKA
QEFDIGVYFEANGHGTALFSTAVEMKIKQSAEQLEDKKRKAAKMLENIIDLFNQAAGDAI
SDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVQVADRRVISTTDAERQAVTPPGLQEA
INDLVKKYKLSRAFVRPSGTEDVVRVYAEADSQESADHLAHEVSLAVFQLAGGIGERPQP
GF
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| O95394 |
| UniProtKB/Swiss-Prot Entry Name
| AGM1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF102265 |
| GeneCard ID
| PGM3 |
| GenAtlas ID
| PGM3 |
| HGNC ID
| HGNC:8907 |
| References |
|---|
| General References
| Not Available |