<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">1445</id>
  <cancdbp-id>CDBP01444</cancdbp-id>
  <name>Cytochrome P450 2A13</name>
  <uniprot-id>Q16696</uniprot-id>
  <uniprot-name>CP2AD_HUMAN</uniprot-name>
  <enzyme type="boolean">false</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Metal Binding</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>CYP2A13</gene-name>
  <num-residues type="integer">494</num-residues>
  <molecular-weight type="decimal">56687.095</molecular-weight>
  <theoretical-pi type="decimal">9.27</theoretical-pi>
  <general-function>Involved in monooxygenase activity</general-function>
  <specific-function>Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity.
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids>2P85;2PG5;2PG6;2PG7;3T3S;4EJG;4EJH;4EJI</pdb-ids>
  <genbank-gene-id>AF209774</genbank-gene-id>
  <genbank-protein-id nil="true"/>
  <genecard-id>CYP2A13</genecard-id>
  <chromosome-location>19</chromosome-location>
  <locus>19q13.2</locus>
  <geneatlas-id>CYP2A13</geneatlas-id>
  <hgnc-id>HGNC:2608</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:1553</kegg-id>
  <meta-cyc-id></meta-cyc-id>
  <ncbi-sequence-ids>NP_000757.2:NM_000766.4</ncbi-sequence-ids>
  <tissue-specificity>Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea, brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine, spleen, stomach, thymus, or skeletal muscle.
</tissue-specificity>
  <cofactor>Heme group</cofactor>
  <subunit></subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:06:56Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:31:57Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">1</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

