| Identification |
|---|
| HMDB Protein ID
| CDBP01427 |
| Secondary Accession Numbers
| Not Available |
| Name
| Serine/threonine-protein kinase H1 |
| Description
| Not Available |
| Synonyms
|
- PSK-H1
- Protein serine kinase H1
|
| Gene Name
| PSKH1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| Process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Lipid-anchor
- Cytoplasm
- Cytoplasm
- Endoplasmic reticulum membrane
- Golgi apparatus
- cytoskeleton
- Nucleus speckle
- centrosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16q22.1 |
| SNPs
| PSKH1 |
| Gene Sequence
|
>1275 bp
ATGGGCTGTGGGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTG
GTCAAGAAGGTGGAGCCCTTCAGTGGCACTAAGAGTGACGTGTACAAGCACTTCATCACA
GAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACAC
CCCTGCCCCGGTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGG
GCCAGGGTAGCTAAGTACAGGGCCAAGTTTGACCCACGTGTTACAGCTAAGTATGACATC
AAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACC
CGGCAGCCGTATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGT
GAGTCGGAGCTGCGTGTGCTGCGTCGGGTGCGTCATGCCAACATCATCCAGCTGGTGGAG
GTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTC
TTTGACCGCATCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAG
ATGGTGCTGGATGGCGTCCGGTATCTGCATGCACTGGGCATCACACACCGAGACCTCAAA
CCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTC
GGCCTGGCCAGTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACG
CCTGAGTACATTGCCCCAGAAGTCCTGGTCCGCAAGCCATACACCAACTCAGTGGACATG
TGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGAC
AACCGTACCCGGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGCCC
TGGCCTAGTGTGTCCAACCTGGCCAAGGACTTCATTGACCGCCTGCTGACAGTGGACCCT
GGAGCCCGTATGACTGCACTGCAGGCCCTGAGGCACCCGTGGGTGGTGAGCATGGCTGCC
TCTTCATCCATGAAGAACCTGCACCGCTCCATATCCCAGAACCTCCTTAAACGTGCCTCC
TCGCGCTGCCAGAGCACCAAATCTGCCCAGTCCACGCGTTCCAGCCGCTCCACACGCTCC
AATAAGTCACGCCGTGTGCGGGAACGGGAGCTGCGGGAGCTCAACCTGCGCTACCAGCAG
CAATACAATGGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 424 |
| Molecular Weight
| 48034.7 |
| Theoretical pI
| 10.28 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Serine/threonine-protein kinase H1
MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAH
PCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRAT
RQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL
FDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDF
GLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDD
NRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAA
SSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQ
QYNG
|
| External Links |
|---|
| GenBank ID Protein
| 7981277 |
| UniProtKB/Swiss-Prot ID
| P11801 |
| UniProtKB/Swiss-Prot Entry Name
| KPSH1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ272212 |
| GeneCard ID
| PSKH1 |
| GenAtlas ID
| PSKH1 |
| HGNC ID
| HGNC:9529 |
| References |
|---|
| General References
| Not Available |