Cannabis Compound Database: Showing Protein Ephrin type-B receptor 3 (CDBP01399)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP01399

Secondary Accession Numbers

Not Available

Name

Ephrin type-B receptor 3

Description

Not Available

Synonyms

EK2
EPH-like kinase 2
Tyrosine-protein kinase TYRO6
hEK2

Gene Name

EPHB3

Protein Type

Enzyme

Biological Properties

General Function

Involved in ATP binding

Specific Function

Receptor for members of the ephrin-B family. Binds to ephrin-B1 and -B2

GO Classification

Component
integral to plasma membrane
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
ephrin receptor activity
protein binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
Process
cell surface receptor linked signaling pathway
phosphorylation
phosphorus metabolic process
phosphate metabolic process
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
metabolic process
cellular metabolic process
protein amino acid phosphorylation
signaling
signaling pathway

Cellular Location

Membrane
Single-pass type I membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3q21-qter

SNPs

EPHB3

Gene Sequence

>2997 bp
ATGGCCAGAGCCCGCCCGCCGCCGCCGCCGTCGCCGCCGCCGGGGCTTCTGCCGCTGCTC
CCTCCGCTGCTGCTGCTGCCGCTGCTGCTGCTGCCCGCCGGCTGCCGGGCGCTGGAAGAG
ACCCTCATGGACACAAAATGGGTAACATCTGAGTTGGCGTGGACATCTCATCCAGAAAGT
GGGTGGGAAGAGGTGAGTGGCTACGATGAGGCCATGAATCCCATCCGCACATACCAGGTG
TGTAATGTGCGCGAGTCAAGCCAGAACAACTGGCTTCGCACGGGGTTCATCTGGCGGCGG
GATGTGCAGCGGGTCTACGTGGAGCTCAAGTTCACTGTGCGTGACTGCAACAGCATCCCC
AACATCCCCGGCTCCTGCAAGGAGACCTTCAACCTCTTCTACTACGAGGCTGACAGCGAT
GTGGCCTCAGCCTCCTCCCCCTTCTGGATGGAGAACCCCTACGTGAAAGTGGACACCATT
GCACCCGATGAGAGCTTCTCGCGGCTGGATGCCGGCCGTGTCAACACCAAGGTGCGCAGC
TTTGGGCCACTTTCCAAGGCTGGCTTCTACCTGGCCTTCCAGGACCAGGGCGCCTGCATG
TCGCTCATCTCCGTGCGCGCCTTCTACAAGAAGTGTGCATCCACCACCGCAGGCTTCGCA
CTCTTCCCCGAGACCCTCACTGGGGCGGAGCCCACCTCGCTGGTCATTGCTCCTGGCACC
TGCATCCCTAACGCCGTGGAGGTGTCGGTGCCACTCAAGCTCTACTGCAACGGCGATGGG
GAGTGGATGGTGCCTGTGGGTGCCTGCACCTGTGCCACCGGCCATGAGCCAGCTGCCAAG
GAGTCCCAGTGCCGCCCCTGTCCCCCTGGGAGCTACAAGGCGAAGCAGGGAGAGGGGCCC
TGCCTCCCATGTCCCCCCAACAGCCGTACCACCTCCCCAGCCGCCAGCATCTGCACCTGC
CACAATAACTTCTACCGTGCAGACTCGGACTCTGCGGACAGTGCCTGTACCACCGTGCCA
TCTCCACCCCGAGGTGTGATCTCCAATGTGAATGAAACCTCACTGATCCTCGAGTGGAGT
GAGCCCCGGGACCTGGGTGGCCGGGATGACCTCCTGTACAATGTCATCTGCAAGAAGTGC
CATGGGGCTGGAGGGGCCTCAGCCTGCTCACGCTGTGATGACAACGTGGAGTTTGTGCCT
CGGCAGCTGGGCCTGACGGAGCGCCGGGTCCACATCAGCCATCTGCTGGCCCACACGCGC
TACACCTTTGAGGTGCAGGCGGTCAACGGTGTCTCGGGCAAGAGCCCTCTGCCGCCTCGT
TATGCGGCCGTGAATATCACCACAAACCAGGCTGCCCCGTCTGAAGTGCCCACACTACGC
CTGCACAGCAGCTCAGGCAGCAGCCTCACCCTATCCTGGGCACCCCCAGAGCGGCCCAAC
GGAGTCATCCTGGACTACGAGATGAAGTACTTTGAGAAGAGCGAGGGCATCGCCTCCACA
GTGACCAGCCAGATGAACTCCGTGCAGCTGGACGGGCTTCGGCCTGACGCCCGCTATGTG
GTCCAGGTCCGTGCCCGCACAGTAGCTGGCTATGGGCAGTACAGCCGCCCTGCCGAGTTT
GAGACCACAAGTGAGAGAGGCTCTGGGGCCCAGCAGCTCCAGGAGCAGCTTCCCCTCATC
GTGGGCTCCGCTACAGCTGGGCTTGTCTTCGTGGTGGCTGTCGTGGTCATCGCTATCGTC
TGCCTCAGGAAGCAGCGACACGGCTCTGATTCGGAGTACACGGAGAAGCTGCAGCAGTAC
ATTGCTCCTGGAATGAAGGTTTATATTGACCCTTTTACCTACGAGGACCCTAATGAGGCT
GTTCGGGAGTTTGCCAAGGAGATCGACGTGTCCTGCGTCAAGATCGAGGAGGTGATCGGA
GCTGGGGAATTTGGGGAAGTGTGCCGTGGTCGACTGAAACAGCCTGGCCGCCGAGAGGTG
TTTGTGGCCATCAAGACGCTGAAGGTGGGCTACACCGAGAGGCAGCGGCGGGACTTCCTA
AGCGAGGCCTCCATCATGGGTCAGTTTGATCACCCCAATATAATCCGGCTCGAGGGCGTG
GTCACCAAAAGTCGGCCAGTTATGATCCTCACTGAGTTCATGGAAAACTGCGCCCTGGAC
TCCTTCCTCCGGCTCAACGATGGGCAGTTCACGGTCATCCAGCTGGTGGGCATGTTGCGG
GGCATTGCTGCCGGCATGAAGTACCTGTCCGAGATGAACTATGTGCACCGCGACCTGGCT
GCTCGCAACATCCTTGTCAACAGCAACCTGGTCTGCAAAGTCTCAGACTTTGGCCTCTCC
CGCTTCCTGGAGGATGACCCCTCCGATCCTACCTACACCAGTTCCCTGGGCGGGAAGATC
CCCATCCGCTGGACTGCCCCAGAGGCCATAGCCTATCGGAAGTTCACTTCTGCTAGTGAT
GTCTGGAGCTACGGAATTGTCATGTGGGAGGTCATGAGCTATGGAGAGCGACCCTACTGG
GACATGAGCAACCAGGATGTCATCAATGCCGTGGAGCAGGATTACCGGCTGCCACCACCC
ATGGACTGTCCCACAGCACTGCACCAGCTCATGCTGGACTGCTGGGTGCGGGACCGGAAC
CTCAGGCCCAAATTCTCCCAGATTGTCAATACCCTGGACAAGCTCATCCGCAATGCTGCC
AGCCTCAAGGTCATTGCCAGCGCTCAGTCTGGCATGTCACAGCCCCTCCTGGACCGCACG
GTCCCAGATTACACAACCTTCACGACAGTTGGTGATTGGCTGGATGCCATCAAGATGGGG
CGGTACAAGGAGAGCTTCGTCAGTGCGGGGTTTGCATCTTTTGACCTGGTGGCCCAGATG
ACGGCAGAAGACCTGCTCCGTATTGGGGTCACCCTGGCCGGCCACCAGAAGAAGATCCTG
AGCAGTATCCAGGACATGCGGCTGCAGATGAACCAGACGCTGCCTGTGCAGGTCTGA

Protein Properties

Number of Residues

998

Molecular Weight

110328.8

Theoretical pI

6.23

Pfam Domain Function

SAM_1 (PF00536 )
Pkinase_Tyr (PF07714 )
Ephrin_lbd (PF01404 )
fn3 (PF00041 )
GCC2_GCC3 (PF07699 )

Signals

["1-33"]

Transmembrane Regions

["560-580"]

Protein Sequence

>Ephrin type-B receptor 3
MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES
GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP
NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS
FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT
CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP
CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS
EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR
YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN
GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF
ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY
IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV
FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD
SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS
RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW
DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA
SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM
TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV

External Links

GenBank ID Protein

31418208

UniProtKB/Swiss-Prot ID

P54753

UniProtKB/Swiss-Prot Entry Name

EPHB3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

BC052968

GeneCard ID