Cannabis Compound Database: Showing Protein Tyrosine-protein kinase Fer (CDBP01389)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP01389

Secondary Accession Numbers

Not Available

Name

Tyrosine-protein kinase Fer

Description

Not Available

Synonyms

Proto-oncogene c-Fer
Tyrosine kinase 3
p94-Fer

Gene Name

FER

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein kinase activity

Specific Function

Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control

GO Classification

Function
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
binding
catalytic activity
Process
phosphorylation
phosphorus metabolic process
phosphate metabolic process
peptidyl-tyrosine phosphorylation
metabolic process
cellular metabolic process
protein amino acid phosphorylation

Cellular Location

Nucleus
Cytoplasm

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:5

Locus

5q21

SNPs

FER

Gene Sequence

>2469 bp
ATGGGGTTTGGGAGTGACCTGAAGAATTCACATGAAGCAGTGTTAAAATTGCAAGACTGG
GAATTACGGTTACTGGAAACAGTAAAGAAATTTATGGCCCTGAGAATAAAAAGTGATAAA
GAATATGCATCTACTTTACAGAACCTTTGTAATCAAGTTGATAAGGAAAGTACTGTCCAA
ATGAATTATGTCAGCAACGTATCCAAGTCTTGGCTACTTATGATTCAGCAGACAGAACAA
CTTAGTAGGATAATGAAGACACATGCAGAGGACTTGAACTCTGGACCTTTACACAGGCTC
ACCATGATGATTAAGGACAAGCAGCAGGTGAAGAAAAGTTACATAGGTGTTCATCAGCAG
ATAGAGGCAGAGATGATCAAGGTTACCAAAACAGAATTGGAGAAGTTAAAATGCAGCTAT
AGACAATTAATAAAAGAAATGAATTCTGCCAAAGAGAAATATAAAGAAGCTTTAGCTAAA
GGGAAGGAAACTGAAAAGGCCAAGGAACGATACGACAAAGCCACAATGAAACTTCATATG
TTGCACAATCAGTATGTATTGGCGTTGAAAGGGGCACAGCTCCATCAGAATCAGTATTAT
GATATCACACTTCCCCTGCTTCTGGACTCCTTACAAAAGATGCAAGAAGAAATGATAAAA
GCACTCAAAGGTATATTTGATGAATACAGCCAGATAACCAGTCTTGTCACAGAGGAAATA
GTGAATGTCCATAAAGAGATTCAAATGTCGGTTGAACAGATAGATCCTAGTACAGAATAC
AATAATTTCATAGATGTTCACAGAACAACGGCTGCTAAAGAACAAGAAATAGAGTTTGAT
ACTTCCTTACTGGAAGAAAATGAAAATCTTCAGGCAAATGAGATCATGTGGAATAACTTA
ACAGCAGAAAGTTTGCAAGTAATGTTGAAAACGTTAGCGGAAGAACTTATGCAAACACAG
CAGATGCTTTTAAACAAGGAGGAGGCTGTTTTGGAGTTAGAGAAGAGAATTGAAGAATCT
TCTGAAACTTGTGAGAAGAAGTCTGATATTGTGCTTCTGCTAAGCCAAAAACAGGCACTT
GAAGAACTGAAACAGTCAGTCCAGCAGCTGAGATGCACTGAAGCAAAGTTTTCAGCACAG
AAGGAATTACTAGAGCAAAAAGTGCAAGAAAATGATGGGAAAGAGCCACCTCCAGTAGTA
AATTATGAAGAAGATGCACGATCAGTTACATCTATGGAAAGAAAGGAGAGGCTATCCAAA
TTTGAATCTATTCGTCATTCAATTGCTGGAATAATTAGGTCTCCAAAATCTGCAGTGGGC
TCTTCAGCACTTTCTGATATGATCTCCATCAGTGAGAAGCCTTTGGCAGAACAGGACTGG
TACCATGGTGCAATTCCCAGAATAGAAGCTCAAGAACTGTTAAAAAAACAAGGAGACTTT
TTGGTGCGAGAGAGTCATGGGAAACCTGGTGAATATGTCCTTTCTGTATATTCTGATGGA
CAGAGGAGACATTTTATCATACAATATGTTGATAACATGTATCGATTCGAGGGCACTGGG
TTTTCAAACATTCCTCAACTTATAGATCATCACTATACAACAAAACAGGTCATCACTAAG
AAATCAGGTGTAGTTCTGCTGAATCCTATTCCTAAGGACAAGAAATGGATTCTCAGTCAT
GAAGATGTCATATTGGGAGAATTACTGGGCAAGGGAAATTTTGGTGAAGTATATAAGGGC
ACATTAAAGGATAAAACTTCTGTTGCTGTTAAAACATGTAAAGAAGATCTTCCTCAGGAA
TTGAAAATAAAATTTTTACAAGAAGCCAAAATTCTCAAGCAATATGATCATCCCAATATT
GTCAAACTTATAGGAGTTTGCACACAAAGACAGCCTGTCTACATCATTATGGAACTGGTT
TCAGGAGGTGATTTCCTCACCTTTCTGAGAAGGAAGAAGGATGAACTAAAACTCAAACAG
TTAGTGAAATTTTCATTAGACGCTGCTGCTGGTATGTTGTATCTCGAGAGTAAAAACTGT
ATACACAGGGACCTTGCTGCAAGAAACTGCCTGGTAGGTGAAAATAATGTTCTGAAAATC
AGTGACTTTGGAATGTCTCGTCAAGAGGATGGTGGAGTGTATTCATCTTCTGGCTTAAAG
CAGATTCCCATTAAATGGACAGCACCGGAAGCTCTTAATTATGGGAGATACAGTTCAGAG
AGTGACGTGTGGAGCTTTGGCATCCTTCTCTGGGAGACCTTCAGCTTAGGGGTTTGTCCG
TACCCTGGAATGACAAATCAGCAAGCAAGAGAGCAAGTAGAAAGAGGATACCGGATGTCA
GCTCCCCAGCACTGTCCAGAGGATATTTCCAAAATCATGATGAAGTGTTGGGATTATAAA
CCTGAAAATCGCCCTAAGTTCAGTGAACTTCAGAAAGAGCTCACTATCATCAAGAGAAAA
CTCACATAG

Protein Properties

Number of Residues

822

Molecular Weight

94637.3

Theoretical pI

7.15

Pfam Domain Function

SH2 (PF00017 )
Pkinase_Tyr (PF07714 )
FCH (PF00611 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Tyrosine-protein kinase Fer
MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT

External Links

GenBank ID Protein

339715

UniProtKB/Swiss-Prot ID

P16591

UniProtKB/Swiss-Prot Entry Name

FER_HUMAN

PDB IDs

Not Available

GenBank Gene ID

J03358

GeneCard ID