Identification |
HMDB Protein ID
| CDBP01379 |
Secondary Accession Numbers
| Not Available |
Name
| V-type proton ATPase subunit e 1 |
Description
| Not Available |
Synonyms
|
- V-ATPase 9.2 kDa membrane accessory protein
- V-ATPase M9.2 subunit
- V-ATPase subunit e 1
- Vacuolar proton pump subunit e 1
|
Gene Name
| ATP6V0E1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in hydrogen ion transmembrane transporter activity |
Specific Function
| Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells |
GO Classification
|
Component |
macromolecular complex |
protein complex |
proton-transporting two-sector atpase complex, proton-transporting domain |
proton-transporting v-type atpase, v0 domain |
Function |
hydrogen ion transmembrane transporter activity |
transporter activity |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
ion transmembrane transporter activity |
cation transmembrane transporter activity |
inorganic cation transmembrane transporter activity |
monovalent inorganic cation transmembrane transporter activity |
Process |
establishment of localization |
transport |
purine nucleotide metabolic process |
energy coupled proton transport, against electrochemical gradient |
purine nucleotide biosynthetic process |
atp hydrolysis coupled proton transport |
purine nucleoside triphosphate biosynthetic process |
atp biosynthetic process |
purine ribonucleoside triphosphate biosynthetic process |
metabolic process |
nitrogen compound metabolic process |
cellular nitrogen compound metabolic process |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
nucleobase, nucleoside and nucleotide metabolic process |
nucleoside phosphate metabolic process |
nucleotide metabolic process |
atp synthesis coupled proton transport |
hydrogen transport |
proton transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q35.1 |
SNPs
| ATP6V0E1 |
Gene Sequence
|
>246 bp
ATGGCGTATCACGGCCTCACTGTGCCTCTCATTGTGATGAGCGTGTTCTGGGGCTTCGTC
GGCTTCTTGGTGCCTTGGTTCATCCCTAAGGGTCCTAACCGGGGAGTTATCATTACCATG
TTGGTGACCTGTTCAGTTTGCTGCTATCTCTTTTGGCTGATTGCAATTCTGGCCCAACTC
AACCCTCTCTTTGGACCGCAATTGAAAAATGAAACCATCTGGTATCTGAAGTATCATTGG
CCTTGA
|
Protein Properties |
Number of Residues
| 81 |
Molecular Weight
| 9374.3 |
Theoretical pI
| 8.87 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>V-type proton ATPase subunit e 1
MAYHGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQL
NPLFGPQLKNETIWYLKYHWP
|
External Links |
GenBank ID Protein
| 2584789 |
UniProtKB/Swiss-Prot ID
| O15342 |
UniProtKB/Swiss-Prot Entry Name
| VA0E1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| Y15286 |
GeneCard ID
| ATP6V0E1 |
GenAtlas ID
| ATP6V0E1 |
HGNC ID
| HGNC:863 |
References |
General References
| Not Available |