| Identification |
|---|
| HMDB Protein ID
| CDBP01348 |
| Secondary Accession Numbers
| Not Available |
| Name
| Tyrosine-protein kinase RYK |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RYK |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| Potential growth factor receptor protein tyrosine kinase |
| GO Classification
|
| Component |
| integral to plasma membrane |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein binding |
| wnt-protein binding |
| protein kinase activity |
| protein tyrosine kinase activity |
| transmembrane receptor protein tyrosine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| wnt receptor signaling pathway |
| protein amino acid phosphorylation |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q22 |
| SNPs
| RYK |
| Gene Sequence
|
>1824 bp
ATGCGTGGGGCGGCGCGGCTGGGGCGGCCGGGCCGGAGTTGCCTCCCGGGGGCCCGCGGC
CTGAGGGCCCCGCCGCCGCCGCCGCTGCTGCTTCTGCTTGCGCTGTTGCCGCTGCTGCCC
GCGCCTGGCGCTGCCGCCGCCCCCGCCCCGCGGCCCCCGGAGCTGCAGTCGGCTTCCGCG
GGGCCCAGCGTGAGTCTCTACCTGAGCGAGGACGAGGTGCGCCGGCTGATCGGTCTTGAT
GCAGAACTTTATTATGTGAGAAATGACCTTATTAGTCACTACGCTCTATCCTTTAGTCTG
TTAGTACCCAGTGAGACAAATTTCCTGCACTTCACCTGGCATGCGAAGTCCAAGGTTGAA
TATAAGCTGGGATTCCAAGTGGACAATGTTTTGGCAATGGATATGCCCCAGGTCAACATT
TCTGTTCAGGGGGAAGTTCCACGCACTTTATCAGTGTTTCGGGTAGAGCTTTCCTGTACT
GGCAAAGTAGATTCTGAAGTTATGATACTAATGCAGCTCAACTTGACAGTAAATTCTTCA
AAAAATTTTACCGTCTTAAATTTTAAACGAAGGAAAATGTGCTACAAAAAACTTGAAGAA
GTAAAAACTTCAGCCTTGGACAAAAACACTAGCAGAACTATTTATGATCCTGTACATGCA
GCTCCAACCACTTCTACGCGTGTGTTTTATATTAGTGTAGGGGTTTGTTGTGCAGTAATA
TTTCTCGTAGCAATAATATTAGCTGTTTTGCACCTTCATAGTATGAAAAGGATTGAACTG
GATGACAGCATTAGTGCCAGCAGTAGTTCCCAAGGGCTGTCTCAGCCATCCACCCAGACG
ACTCAGTATCTGAGAGCAGACACGCCCAACAATGCAACTCCTATCACCAGTTATCCTACC
TTGCGGATAGAGAAGAACGACTTGAGAAGTGTCACTCTTTTGGAGGCCAAAGGCAAGGTG
AAGGATATAGCAATATCCAGAGAGAGGATAACTCTAAAAGATGTACTCCAAGAAGGTACT
TTTGGGCGTATTTTCCATGGGATTTTAATAGATGAAAAAGATCCAAATAAAGAAAAACAA
GCATTTGTCAAAACAGTTAAAGATCAAGCTTCTGAAATTCAGGTGACAATGATGCTCACT
GAAAGTTGTAAGCTGCGAGGTCTTCATCACAGAAATCTTCTTCCTATTACTCATGTGTGT
ATAGAAGAAGGAGAAAAGCCCATGGTGATATTGCCTTACATGAATTGGGGGAATCTTAAA
TTGTTTTTACGACAGTGCAAGTTAGTAGAGGCCAATAATCCACAGGCAATTTCTCAGCAA
GACCTGGTACACATGGCTATTCAGATTGCCTGTGGAATGAGCTACCTGGCCAGAAGGGAA
GTCATCCACAAAGACCTGGCTGCCAGGAACTGTGTCATTGATGACACACTTCAAGTTAAG
ATCACAGACAATGCCCTCTCCAGAGACTTGTTCCCCATGGACTATCACTGTCTGGGGGAC
AATGAAAACAGGCCAGTTCGTTGGATGGCTCTTGAAAGTCTGGTTAATAACGAGTTCTCT
AGCGCTAGTGATGTGTGGGCCTTTGGAGTGACGCTGTGGGAACTCATGACTCTGGGCCAG
ACTCCCTACGTGGACATTGACCCCTTCGAGATGGCCGCATACCTGAAAGATGGTTACCGA
ATAGCCCAGCCAATCAACTGTCCTGATGAATTATTTGCTGTGATGGCCTGTTGCTGGGCC
TTAGATCCAGAGGAGAGGCCCAAGTTTCAGCAGCTGGTACAGTGCCTAACAGAGTTTCAT
GCAGCCCTGGGGGCCTACGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 604 |
| Molecular Weight
| 67506.4 |
| Theoretical pI
| 7.61 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Tyrosine-protein kinase RYK
MRGAARLGRPGRSCLPGPALRAAAAPALLLARCAVAAAAGLRAAARPRPPELQSASAGPS
VSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHAKSKVEYKL
GFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSSKNF
TVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLV
AIILAVLHLHNMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSYPTLRI
EKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFV
KTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFL
RQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITD
NALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPY
VDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAAL
GAYV
|
| External Links |
|---|
| GenBank ID Protein
| 54607018 |
| UniProtKB/Swiss-Prot ID
| P34925 |
| UniProtKB/Swiss-Prot Entry Name
| RYK_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| RYK |
| GenAtlas ID
| RYK |
| HGNC ID
| HGNC:10481 |
| References |
|---|
| General References
| Not Available |