Identification |
HMDB Protein ID
| CDBP01340 |
Secondary Accession Numbers
| Not Available |
Name
| Potassium-transporting ATPase subunit beta |
Description
| Not Available |
Synonyms
|
- Gastric H(+)/K(+) ATPase subunit beta
- Proton pump beta chain
|
Gene Name
| ATP4B |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in sodium:potassium-exchanging ATPase activity |
Specific Function
| Not Available |
GO Classification
|
Component |
membrane |
cell part |
Function |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
ion transmembrane transporter activity |
cation transmembrane transporter activity |
inorganic cation transmembrane transporter activity |
monovalent inorganic cation transmembrane transporter activity |
transporter activity |
potassium ion transmembrane transporter activity |
potassium-transporting atpase activity |
sodium:potassium-exchanging atpase activity |
Process |
nucleoside phosphate metabolic process |
nucleotide metabolic process |
sodium ion transport |
establishment of localization |
transport |
monovalent inorganic cation transport |
potassium ion transport |
ion transport |
purine nucleotide metabolic process |
atp biosynthetic process |
purine nucleotide biosynthetic process |
cation transport |
purine nucleoside triphosphate biosynthetic process |
purine ribonucleoside triphosphate biosynthetic process |
metabolic process |
nitrogen compound metabolic process |
cellular nitrogen compound metabolic process |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
nucleobase, nucleoside and nucleotide metabolic process |
|
Cellular Location
|
- Membrane
- Single-pass type II membrane protein
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Gastric Acid Production | | Not Available | Esomeprazole Action Pathway | | Not Available | Omeprazole Action Pathway | | Not Available | Lansoprazole Action Pathway | | Not Available | Pantoprazole Action Pathway | | Not Available |
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 13q34 |
SNPs
| ATP4B |
Gene Sequence
|
>876 bp
ATGGCGGCTCTGCAGGAGAAGAAGACGTGTGGCCAGCGCATGGAGGAGTTCCAGCGTTAC
TGCTGGAACCCGGACACGGGGCAGATGCTGGGCCGCACCCTGTCCCGGTGGGTGTGGATC
AGCCTGTACTACGTGGCCTTCTACGTGGTGATGACTGGGCTCTTCGCCCTGTGCCTCTAT
GTGCTGATGCAGACAGTGGACCCGTACACACCGGACTACCAAGACCAGCTACGGTCACCA
GGGGTAACCTTAAGGCCGGATGTTTACGGGGAGAAAGGCCTGGAAATTGTCTACAACGTC
TCTGATAACAGAACCTGGGCAGACCTCACACAGACTCTCCACGCCTTCCTAGCAGGCTAC
TCTCCAGCAGCCCAGGAGGACAGCATCAACTGCACCTCCGAGCAGTACTTCTTCCAGGAG
AGTTTCCGCGCTCCCAACCACACCAAGTTCTCCTGCAAGTTCACGGCAGATATGCTGCAG
AACTGCTCAGGCCTGGCGGATCCCAACTTCGGCTTTGAAGAAGGAAAGCCATGTTTTATT
ATTAAAATGAACAGGATCGTCAAGTTCCTCCCCAGCAACGGCTCGGCCCCCAGAGTGGAC
TGCGCCTTCCTGGACCAGCCCCGCGAGCTCGGCCAGCCGCTGCAGGTCAAGTACTACCCT
CCCAACGGCACCTTCAGTCTGCACTACTTCCCTTATTACGGGAAGAAAGCCCAGCCCCAC
TACAGCAACCCCCTGGTGGCAGCGAAGCTCCTCAACATCCCCAGGAACGCTGAGGTCGCC
ATCGTGTGCAAGGTCATGGCGGAGCACGTGACCTTCAACAATCCCCACGACCCGTATGAA
GGGAAAGTGGAGTTCAAACTCAAGATTGAGAAGTGA
|
Protein Properties |
Number of Residues
| 291 |
Molecular Weight
| 33367.0 |
Theoretical pI
| 7.37 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Potassium-transporting ATPase subunit beta
MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFI
IKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPH
YSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
|
External Links |
GenBank ID Protein
| 4557339 |
UniProtKB/Swiss-Prot ID
| P51164 |
UniProtKB/Swiss-Prot Entry Name
| ATP4B_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_000705.3 |
GeneCard ID
| ATP4B |
GenAtlas ID
| ATP4B |
HGNC ID
| HGNC:820 |
References |
General References
| Not Available |