Identification |
HMDB Protein ID
| CDBP01329 |
Secondary Accession Numbers
| Not Available |
Name
| STE20/SPS1-related proline-alanine-rich protein kinase |
Description
| Not Available |
Synonyms
|
- DCHT
- Serine/threonine-protein kinase 39
- Ste-20-related kinase
|
Gene Name
| STK39 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein kinase activity |
Specific Function
| May act as a mediator of stress-activated signals |
GO Classification
|
Function |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
protein kinase activity |
protein serine/threonine kinase activity |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
Process |
phosphorus metabolic process |
phosphate metabolic process |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
phosphorylation |
|
Cellular Location
|
- Cytoplasm (Probable)
- Nucleus (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 2q24.3 |
SNPs
| STK39 |
Gene Sequence
|
>1644 bp
ATGGCGGAGCCGAGCGGCTCGCCCGTGCACGTCCAGCTTCCCCAGCAGGCGGCCCCGGTG
ACAGCGGCGGCGGCGGCGGCCCCGGCGGCCGCGACAGCAGCGCCGGCCCCGGCAGCTCCC
GCGGCCCCGGCCCCGGCCCCGGCCCCGGCCCCGGCGGCACAGGCTGTCGGCTGGCCCATC
TGCAGGGACGCGTACGAGCTGCAGGAGGTTATCGGCAGTGGAGCTACTGCTGTGGTTCAG
GCAGCCCTATGCAAACCCAGGCAAGAACGTGTAGCAATAAAACGGATCAACTTGGAAAAA
TGCCAGACCAGTATGGATGAACTATTAAAAGAAATTCAAGCCATGAGTCAGTGCAGCCAT
CCCAACGTAGTGACCTATTACACCTCTTTTGTGGTCAAAGATGAACTTTGGCTGGTCATG
AAATTACTAAGTGGAGGTTCAATGTTGGATATCATAAAATACATTGTCAACCGAGGAGAA
CACAAGAATGGAGTTTTGGAAGAGGCAATAATAGCAACAATTTTTAAAGAGGTTTTGGAA
GGCTTAGACTATCTACACAGAAACGGTCAGATTCACAGGGATTTGAAAGCTGGTAATATT
CTTCTGGGTGAGGATGGTTCAGTACAAATAGCAGATTTTGGGGTAAGTGCGTTCCTAGCA
ACAGGGGGTGATGTTACCCGAAATAAAGTAAGAAAAACATTCGTTGGCACCCCATGTTGG
ATGGCTCCTGAAGTCATGGAACAGGTGAGAGGCTATGACTTCAAGGCTGACATGTGGAGT
TTTGGAATAACTGCCATTGAATTAGCAACAGGAGCAGCGCCTTATCACAAATATCCTCCC
ATGAAAGTGTTAATGTTGACTTTGCAAAATGATCCACCCACTTTGGAAACAGGGGTAGAG
GATAAAGAAATGATGAAAAAGTACGGCAAGTCCTTTAGAAAATTACTTTCACTGTGTCTT
CAGAAAGATCCTTCCAAAAGGCCCACAGCAGCAGAACTTTTAAAATGCAAATTCTTCCAG
AAAGCCAAGAACAGAGAGTACCTGATTGAGAAGCTGCTTACAAGAACACCAGACATAGCC
CAAAGAGCCAAAAAGGTAAGAAGAGTTCCTGGGTCAAGTGGTCACCTTCATAAAACCGAA
GACGGGGACTGGGAGTGGAGTGACGACGAGATGGATGAGAAGAGCGAAGAAGGGAAAGCA
GCTTTTTCTCAGGAAAAGTCACGAAGAGTAAAAGAAGAAAATCCAGAGATTGCAGTGAGT
GCCAGCACCATCCCCGAACAAATACAGTCCCTCTCTGTGCACGACTCTCAGGGCCCACCC
AATGCTAATGAAGACTACAGAGAAGCTTCTTCTTGTGCCGTGAACCTCGTTTTGAGATTA
AGAAACTCCAGAAAGGAACTTAATGACATACGATTTGAGTTTACTCCAGGAAGAGATACA
GCAGATGGTGTATCTCAGGAGCTCTTCTCTGCTGGCTTGGTGGATGGTCACGATGTAGTT
ATAGTGGCTGCTAATTTACAGAAGATTGTAGATGATCCCAAAGCTTTAAAAACATTGACA
TTTAAGTTGGCTTCTGGCTGTGATGGGTCGGAGATTCCTGATGAAGTGAAGCTGATTGGG
TTTGCTCAGTTGAGTGTCAGCTGA
|
Protein Properties |
Number of Residues
| 547 |
Molecular Weight
| 59641.6 |
Theoretical pI
| 6.21 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>STE20/SPS1-related proline-alanine-rich protein kinase
MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAPAAQAVGWPI
CRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSH
PNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLE
GLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCW
MAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVE
DKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIA
QRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVS
ASTIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDT
ADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIG
FAQLSVS
|
External Links |
GenBank ID Protein
| 4103971 |
UniProtKB/Swiss-Prot ID
| Q9UEW8 |
UniProtKB/Swiss-Prot Entry Name
| STK39_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF030403 |
GeneCard ID
| STK39 |
GenAtlas ID
| STK39 |
HGNC ID
| HGNC:17717 |
References |
General References
| Not Available |